A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placental phenotype in a rabbit model

D Rousseau-Ralliard, A Couturier-Tarrade… - Molecular and cellular …, 2019 - Elsevier
Tight metabolic control of type-1 diabetes is essential during gestation, but it could be crucial
during the periconception period. Feto-placental consequences of maternal type-1 diabetes …

A lipidomic analysis of placenta in preeclampsia: evidence for lipid storage

SHJ Brown, SR Eather, DJ Freeman, BJ Meyer… - Plos one, 2016 - journals.plos.org
In preeclampsia, maternal insulin resistance leads to defective expansion of adipocytes,
enhanced adipocyte lipolysis, up-regulation of very low density lipoprotein synthesis …

Placental function in maternal-fetal fat transport in diabetes

E Shafrir, V Barash - Neonatology, 1987 - karger.com
High levels of triglycerides (TG) and free fatty acids (FFA) in maternal plasma, in diabetes,
promote fat passage to the fetus. In the streptozotocin-diabetic rat a significant correlation …

Dietary fat impacts fetal growth and metabolism: uptake of chylomicron remnant core lipids by the placenta

SL Rebholz, KT Burke, Q Yang… - American Journal of …, 2011 - journals.physiology.org
The fetus requires significant energy for growth and development. Although glucose is a
major source of energy for the fetus, other maternal nutrients also appear to promote growth …

Fetal and maternal lipoprotein metabolism in human pregnancy complicated by type I diabetes mellitus

MD Kilby, RH Neary, MI Mackness… - The Journal of Clinical …, 1998 - academic.oup.com
Serum lipid, apolipoprotein concentration, and lipoprotein composition were determined in
maternal and umbilical venous cord blood at delivery by elective Cesarean section (CS) in …

Effects of obesity and gestational diabetes mellitus on placental phospholipids

O Uhl, H Demmelmair, MT Segura, J Florido… - Diabetes research and …, 2015 - Elsevier
Gestational diabetes mellitus (GDM) is associated with adverse effects in the offspring. The
composition of placental glycerophospholipids (GPL) is known to be altered in GDM and …

Placental LPL gene expression is increased in severe intrauterine growth-restricted pregnancies

S Tabano, G Alvino, P Antonazzo, FR Grati… - Pediatric …, 2006 - nature.com
Intrauterine growth restriction (IUGR) is associated with reduced placental supply of
nutrients to the fetus. Lipoprotein lipase (LPL) mediates the hydrolysis of triglycerides from …

Maternal and fetal serum lipid and lipoprotein concentrations and compositions in type 1 diabetic pregnancy: relationship with maternal glycemic control

H Merzouk, S Madani, N Korso, M Bouchenak… - Journal of Laboratory …, 2000 - Elsevier
The aim of this study was to determine maternal and fetal lipoprotein profiles in type 1
diabetic pregnancies differing in glycemic control. Serum lipid, apolipoprotein, and …

Lipid metabolism in pregnancy and its consequences in the fetus and newborn

E Herrera - Endocrine, 2002 - Springer
During early pregnancy there is an increase in body fat accumulation, associated with both
hyperphagia and increased lipogenesis. During late pregnancy there is an accelerated …

Elevated lipoprotein lipids and gestational hormones in women with diet-treated gestational diabetes mellitus compared to healthy pregnant controls

SC Couch, EH Philipson, RB Bendel, LM Pujda… - Journal of Diabetes and …, 1998 - Elsevier
The objective of this study was to describe plasma and lipoprotein perturbations in
gestational diabetes mellitus (GDM) compared to controls, and determine if alterations in …