[HTML][HTML] Species-specific adaptations of trypanosome morphology and motility to the mammalian host

JL Bargul, J Jung, FA McOdimba, CO Omogo… - PLoS …, 2016 - journals.plos.org
African trypanosomes thrive in the bloodstream and tissue spaces of a wide range of
mammalian hosts. Infections of cattle cause an enormous socio-economic burden in sub …

[HTML][HTML] Impact of microscopic motility on the swimming behavior of parasites: straighter trypanosomes are more directional

S Uppaluri, J Nagler, E Stellamanns… - PLoS computational …, 2011 - journals.plos.org
Microorganisms, particularly parasites, have developed sophisticated swimming
mechanisms to cope with a varied range of environments. African Trypanosomes, causative …

[HTML][HTML] Trypanosome motion represents an adaptation to the crowded environment of the vertebrate bloodstream

N Heddergott, T Krüger, SB Babu, A Wei… - PLoS …, 2012 - journals.plos.org
Blood is a remarkable habitat: it is highly viscous, contains a dense packaging of cells and
perpetually flows at velocities varying over three orders of magnitude. Only few pathogens …

Parasites in motion: flagellum-driven cell motility in African trypanosomes

KL Hill - Current opinion in microbiology, 2010 - Elsevier
Motility of the sleeping sickness parasite, Trypanosoma brucei, impacts disease
transmission and pathogenesis. Trypanosome motility is driven by a flagellum that harbors a …

[HTML][HTML] Visualizing trypanosomes in a vertebrate host reveals novel swimming behaviours, adaptations and attachment mechanisms

E Doro, SH Jacobs, FR Hammond, H Schipper… - Elife, 2019 - elifesciences.org
Trypanosomes are important disease agents of humans, livestock and cold-blooded
species, including fish. The cellular morphology of trypanosomes is central to their motility …

[HTML][HTML] The limits on trypanosomatid morphological diversity

RJ Wheeler, E Gluenz, K Gull - PLoS One, 2013 - journals.plos.org
Cell shape is one, often overlooked, way in which protozoan parasites have adapted to a
variety of host and vector environments and directional transmissions between these …

Motility and more: the flagellum of Trypanosoma brucei

G Langousis, KL Hill - Nature Reviews Microbiology, 2014 - nature.com
Trypanosoma brucei is a pathogenic unicellular eukaryote that infects humans and other
mammals in sub-Saharan Africa. A central feature of trypanosome biology is the single …

Biology and mechanism of trypanosome cell motility

KL Hill - Eukaryotic Cell, 2003 - Am Soc Microbiol
Movement of microbial pathogens plays an important role in pathogen biology, host-
pathogen interaction, and disease pathogenesis. Microbial pathogens employ a variety of …

Flagellar and ciliary beating in trypanosome motility

C Gadelha, B Wickstead, K Gull - Cell motility and the …, 2007 - Wiley Online Library
The single flagellum of Leishmania and Trypanosoma parasites is becoming an increasingly
attractive model for the analysis of flagellar function—driven largely by the abundance of …

Flagellum couples cell shape to motility in Trypanosoma brucei

SY Sun, JT Kaelber, M Chen, X Dong… - Proceedings of the …, 2018 - National Acad Sciences
In the unicellular parasite Trypanosoma brucei, the causative agent of human African
sleeping sickness, complex swimming behavior is driven by a flagellum laterally attached to …