Inhibitory effects of brain chondroitin sulfate proteoglycans on neurite outgrowth from PC12D cells

A Oohira, F Matsui, R Katoh-Semba - Journal of Neuroscience, 1991 - Soc Neuroscience
Soluble chondroitin sulfate proteoglycans (CSPGs), prepared from 10-d-old rat brain, were
added to the culture medium of PC12D cells containing NGF to examine the effects on NGF …

Core protein of chondroitin sulfate proteoglycan promotes neurite outgrowth from cultured neocortical neurons

N Iijima, A Oohira, T Mori, K Kitabatake… - Journal of …, 1991 - Wiley Online Library
Chondroitin sulfate proteoglycan (CS‐PG) was purified from rat brain and examined for its
effect on neurite outgrowth in primary cultures of embryonic rat neocortical neurons. Neurite …

Chondroitin sulphate proteoglycans in the rat brain: candidates for axon barriers of sensory neurons and the possible modification by laminin of their actions

R Katoh‐Semba, M Matsuda, K Kato… - European Journal of …, 1995 - Wiley Online Library
The addition of chondroitin sulphate proteoglycans (CSPGs), purified from the rat brain, to
the culture medium of PC12D cells inhibited their proliferation and neurite outgrowth …

Chondroitin sulphate proteoglycans in the central nervous system: changes and synthesis after injury

F Properzi, RA Asher, JW Fawcett - Biochemical Society …, 2003 - portlandpress.com
Chondroitin sulphate proteoglycans (CSPGs) are up-regulated in the central nervous system
after injury, specifically around the lesion site where the glial scar forms. This structure …

[HTML][HTML] Effect of chondroitin sulfate proteoglycans on neuronal cell adhesion, spreading and neurite growth in culture

J Jin, S Tilve, Z Huang, L Zhou… - Neural Regeneration …, 2018 - journals.lww.com
As one major component of extracellular matrix (ECM) in the central nervous system,
chondroitin sulfate proteoglycans (CSPGs) have long been known as inhibitors enriched in …

Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan

CL Dou, JM Levine - Journal of Neuroscience, 1994 - Soc Neuroscience
The chondroitin sulfate proteoglycans (CSPGs) have been implicated as both positive and
negative modulators of axonal growth; however, the functional properties of only a few …

Nervous system–derived chondroitin sulfate proteoglycans regulate growth cone morphology and inhibit neurite outgrowth: A light, epifluorescence, and electron …

DM Snow, N Mullins, DL Hynds - Microscopy research and …, 2001 - Wiley Online Library
Proteoglycans influence aging and plasticity in the nervous system. Particularly prominent
are the chondroitin sulfate proteoglycans (CSPGs), which are generally inhibitory to neurite …

Purification of a meningeal cell‐derived chondroitin sulphate proteoglycan with neurotrophic activity for brain neurons and its identification as biglycan

U Junghans, A Koops, A Westmeyer… - European Journal of …, 1995 - Wiley Online Library
Serum‐free cultures of meningeal fibroblasts synthesize and release a chondroitin sulphate
proteoglycan (CSPG) that markedly enhances survival but not adhesion of embryonic rat …

Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes

GM Smith, C Strunz - Glia, 2005 - Wiley Online Library
After injury to the adult central nervous system (CNS), numerous cytokines and growth
factors are released that contribute to reactive gliosis and extracellular matrix production. In …

Chondroitin 4-sulfate proteoglycan forms an extracellular network in human and rat central nervous system

A Bertolotto, G Rocca, D Schiffer - Journal of the neurological sciences, 1990 - Elsevier
Summary Chondroitin 4-sulfate proteoglycan (C4S-PG) was localized both in rat and human
central nervous system (CNS) by monoclonal and polyclonal antisera recognizing the 4 …