Previously, we have found that human islets experimentally transplanted beneath the kidney
capsule have lower vascular density than native islets. This study aimed to investigate …

A large proportion of islets are lost after transplantation partly due to a lack of functional
vasculature. Islets revascularize from host tissue but the process takes up to 2 weeks and …

For their survival and optimal function, pancreatic islets depend posttransplantation on a
rapid and adequate revascularization. Native islets display a marked size-dependent …

Although in a clinical setting islet transplantation is normally performed by percutaneous
intrahepatic infusion, the kidney capsule has been the site of choice in nearly all the studies …

Transplantation of islets into the liver confers several site-specific challenges, including a
delayed vascularization and prevailing hypoxia. The greater omentum has in several …

The blood vessels of the pancreatic islets are of crucial importance for oxygen and
metabolite supply, and dispersal of secreted hormones. In addition to this, endothelial cells …

Background. Pancreatic islets are avascular immediately after transplantation and depend
on revascularization. Recently, the authors found decreased vascular density in mouse …

New blood vessel formation in transplanted islets occurs within 7–14 days post‐
transplantation through both the expansion of donor islet endothelium and ingrowth of blood …

An adequate revascularization is crucial for islet survival and function after transplantation.
Previous studies have suggested that islet revascularization is concluded within 14 days …

Background. We investigated the influence of exocrine tissue contamination on the process
of vascularization of isolated pancreatic islets of Langerhans after free transplantation into …