Abstract The 17β-hydroxysteroid dehydrogenases (17βHSD) gene family comprises
different enzymes involved in the biosynthesis of active steroid hormones. The 17βHSD type …

Abstract 17β-Hydroxysteroid dehydrogenase type 3 (17β-HSD3) is expressed almost
exclusively in the testis and converts Δ4-androstene-3, 17-dione to testosterone. Mutations …

abstract Isozymes of 17β-hydroxysteroid dehydrogenase (17βHSD) regulate levels of
bioactive androgens and estrogens in a variety of tissues. For example, the 17βHSD type 3 …

17β-hydroxysteroid dehydrogenase deficiency is a rare autosomal recessive inherited
disorder of sex development, affecting only 46, XY individuals. It is due to mutations in the …

Steroid 17β-hydroxysteroid dehydrogenase III (17β-HSD3) deficiency is a rare autosomal
recessive disorder that usually presents in patients with a 46, XY karyotype with ambiguous …

The 17-beta-hydroxysteroid dehydrogenase type 3 (17-β-HSD3) enzyme converts
androstenedione to testosterone and is encoded by the HSD17B3 gene. Homozygous or …

β-Hydroxysteroid dehydrogenase type 3 (17βHSD-3) converts Δ4 androstenedione (A) to
testosterone (T) in the testes. This enzyme plays a key role in androgen synthesis and it is …

Background Deficiency of 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) is a rare
autosomal recessive 46, XY disorder of sex development (DSD). It is due to pathogenetic …

Abstract 17β-hydroxysteroid dehydrogenase 3 deficiency consists of a defect in the last
phase of steroidogenesis, in which androstenedione is converted into testosterone and …

Deficiency of 17β-hydroxysteroid dehydrogenase type3 (17β-HSD3) isoenzyme which
catalyzes the synthesis of testosterone from Δ4-androstenedione, is the cause of 46, XY …