[PDF][PDF] The development of metabolic derangement in male offspring after perinatal exposure to di-(2-ethylhexyl) phthalate

Y Yang, M Park, EJ Lee, Y Hong - Biomed. Environ. Sci, 2018 - academia.edu
The prevalence of obesity and type 2 diabetes mellitus (T2DM) has been increasing
throughout the world over the past 20 years. Environmental chemicals known to regulate the …

Associations between prenatal exposure to phthalates and features of the metabolic syndrome in males from childhood into adulthood

YE Berman, DA Doherty, TA Mori, LJ Beilin… - International Journal of …, 2022 - mdpi.com
Phthalate metabolites are detectable within the majority of the population. Evidence
suggests that a prenatal exposure to phthalates may be associated with the subsequent …

[HTML][HTML] The impact of Di-(2-ethylhexyl) Phthalate and Mono (2-ethylhexyl) Phthalate in placental development, function, and pathophysiology

LD Martínez-Razo, A Martínez-Ibarra… - Environment …, 2021 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a chemical widely distributed in the
environment as is extensively used in the plastic industry. DEHP is considered an endocrine …

Early-life exposure to di (2-ethyl-hexyl) phthalate: Role in children with endocrine disorders

F Zeng, L Zhang, F Deng, S Lou - Frontiers in Cell and …, 2023 - frontiersin.org
Di (2-ethyl-hexyl) phthalate (DEHP), one of endocrine-disrupting chemicals (EDCs), has
widespread concern due to its serious health hazards. Exposure to DEHP in the early stage …

Maternal di‐(2‐ethylhexyl) phthalate exposure alters hepatic insulin signal transduction and glucoregulatory events in rat F1 male offspring

G Rajagopal, RS Bhaskaran… - Journal of Applied …, 2019 - Wiley Online Library
Abstract Di‐(2‐ethylhexyl) phthalate (DEHP) is a commonly used plasticizer with endocrine
disrupting properties. Its widespread use resulted in constant human exposure including …

In utero exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate promotes local adipose and systemic inflammation in adult male offspring

E Campioli, DB Martinez-Arguelles… - Nutrition & …, 2014 - nature.com
Background: Di-(2-ethylhexyl) phthalate (DEHP) is a plasticizer used to increase the
flexibility of polyvinyl chloride. DEHP and its active metabolite mono-(2-ethylhexyl) phthalate …

Prenatal exposure to phthalate esters and its impact on child development

N Nidens, M Vogel, A Körner, W Kiess - Best Practice & Research Clinical …, 2021 - Elsevier
Endocrine disruptive chemicals (EDCs) cause adverse health effects through interaction
with endocrine systems. They are classified by chemical structure, effects on specific …

Phthalates exposure and endocrinal effects: an epidemiological review

PC Huang, SH Liou, IK Ho, HC Chiang… - Journal of Food and …, 2012 - jfda-online.com
Phthalates are ubiquitous endocrine disrupters which may cause potential health effects in
general populations. We explored 3 scientific databases (PubMed, Medline, and …

[HTML][HTML] Effects of in utero and lactational exposure to phthalates on reproductive development and glycemic homeostasis in rats

AC Venturelli, KB Meyer, SV Fischer, DH Kita… - Toxicology, 2019 - Elsevier
Prenatal exposure to phthalates is associated with reproductive and metabolic systems
alterations. We investigated the effects of in utero and lactational exposure to Di-(2-ethyl …

Developmental exposure to di (2-ethylhexyl) phthalate impairs endocrine pancreas and leads to long-term adverse effects on glucose homeostasis in the rat

Y Lin, J Wei, Y Li, J Chen, Z Zhou… - American Journal …, 2011 - journals.physiology.org
—Di (2-ethylhexyl) phthalate (DEHP), a typical endocrine-disrupting chemical (EDC), is
widely used as plasticizer. DEHP exposure in humans is virtually ubiquitous, and those …