Reduction in oral corticosteroid use in patients receiving omalizumab for allergic asthma in the real-world setting

GJ Braunstahl, J Chlumský, G Peachey… - Allergy, Asthma & Clinical …, 2013 - Springer
Background Oral corticosteroids (OCS) are commonly administered in patients with severe
persistent allergic asthma. Despite their efficacy, they are associated with a wide variety of …

[HTML][HTML] Omalizumab reduces oral corticosteroid use in patients with severe allergic asthma: real-life data

M Molimard, R Buhl, R Niven, V Le Gros, A Thielen… - Respiratory …, 2010 - Elsevier
BACKGROUND: Long-term oral corticosteroid (OCS) therapy is associated with significant
burden on patients and healthcare resources; treatments that may help reduce their use are …

Effectiveness of omalizumab in reducing corticosteroid burden in patients with moderate to severe persistent allergic asthma

J Karpel, M Massanari, GP Geba, F Kianifard… - Annals of Allergy …, 2010 - Elsevier
BACKGROUND: Asthma guidelines advocate maintaining asthma control while minimizing
corticosteroid exposure. OBJECTIVE: To assess the reduction in corticosteroid burden …

Oral corticosteroid sparing with omalizumab in severe allergic (IgE-mediated) asthma patients

Z Siergiejko, E Świebocka, N Smith… - … medical research and …, 2011 - Taylor & Francis
Background: Long-term oral corticosteroid (OCS) therapy and related adverse events are
associated with a significant burden on patients and healthcare resources. Methods: This …

The real world effect of omalizumab add on therapy for patients with moderate to severe allergic asthma: The ASTERIX Observational study

M Bhutani, WH Yang, J Hébert, F de Takacsy, JL Stril - PLoS One, 2017 - journals.plos.org
Background Omalizumab is a non-steroidal medication indicated for the treatment of poorly
controlled moderate-to-severe allergic asthmatics. This observational study examines the …

Effect of omalizumab on the need for rescue systemic corticosteroid treatment in patients with moderate-to-severe persistent IgE-mediated allergic asthma: a pooled …

WW Busse, M Massanari, F Kianifard… - … medical research and …, 2007 - Taylor & Francis
Background: Allergic asthma is an immunoglobulin E (IgE)-mediated disease characterized
by frequent exacerbations following exposure to relevant allergens that leads to the …

Omalizumab therapy for asthma patients with poor adherence to inhaled corticosteroid therapy

L Hendeles, YR Khan, JJ Shuster, SE Chesrown… - Annals of Allergy …, 2015 - Elsevier
Abstract Background Omalizumab, an anti-IgE monoclonal antibody, is administered by
injection once or twice monthly in offices and clinics. It offers a potential alternative …

A step‐down protocol for omalizumab treatment in oral corticosteroid‐dependent allergic asthma patients

C Domingo, X Pomares, A Navarro… - British journal of …, 2018 - Wiley Online Library
Aims There are no specific criteria for a step‐down or withdrawal dose of omalizumab
(OMA). Our purpose was to evaluate the viability of a protocol for OMAlizumab DOse …

The long-term effectiveness of omalizumab in adult patients with severe allergic asthma: continuous treatment versus boosting treatment

WC Huang, PK Fu, MC Chan, CS Chin… - Journal of clinical …, 2021 - mdpi.com
The implications of boosting Omalizumab treatment (OT) in patients with severe allergic
asthma (SAA) remain unclear. The study aimed to explore and compare the 12-month …

Omalizumab reduces corticosteroid use in patients with severe allergic asthma: real-life experience in Israel

M Rottem - Journal of Asthma, 2012 - Taylor & Francis
Objective. Approved by the FDA in 2003, omalizumab is the first recombinant humanized
monoclonal anti-immunoglobulin E antibody developed for the treatment of allergic asthma …