Big data and tiny proteins: shining a light on the dark corners of the gut microbiome

S Devkota - Nature Reviews Gastroenterology & Hepatology, 2020 - nature.com
In 2019, there have been substantial advances in our understanding of the gut microbiome.
Key developments include an improved gut-on-a-chip system, a search for small proteins …

The gut microbiome: Reaching the promise through discovery—advancing knowledge and discovery of the gut microbiome in the age of precision medicine

BA McCormick, EB Chang - Gastroenterology, 2021 - gastrojournal.org
The gastrointestinal tract is home to nearly a tril-lion microbes that are comprised of bacteria,
viruses, fungi, and other microorganisms which are collectively called the gut microbiome …

[引用][C] Gut microbiome: The cornerstone of life and health

Z Ling, H Xiao, W Chen - Advanced Gut & Microbiome …, 2022 - Wiley Online Library
After the completion of the Human Genome Project in April 2003, scientists realize that
decoding human genome is not enough to understand human biology because there are …

Gut Microbiome and Disorders of the Gastrointestinal Tract

A Hammerhøj, JM Gubatan, OH Nielsen - Microorganisms, 2024 - mdpi.com
The protective intestinal epithelial barrier is constantly exposed to more than 100 trillion
commensal microorganisms (bacteria, archaea, viruses, and fungi), ie, the microbiome …

Next steps after 15 stimulating years of human gut microbiome research

T Clavel, HP Horz, N Segata… - Microbial …, 2022 - Wiley Online Library
Gut microbiome research has bloomed over the past 15 years. We have learnt a lot about
the complex microbial communities that colonize our intestine. Promising avenues of …

From culture to high-throughput sequencing and beyond: a layperson's guide to the “omics” and diagnostic potential of the microbiome

PW O'Toole, B Flemer - Gastroenterology Clinics, 2017 - gastro.theclinics.com
Studies of the community of bacteria in the human intestine have had a major impact on
gastroenterology research in the last decade. As summarized elsewhere in this issue, it is …

Impact of Gut Microbiota on Host by Exploring Proteomics

TE Angel, UK Aryal - Gut Microbiome and Its Impact on Health and …, 2020 - Springer
Microbial colonization of intestine plays an important role in many aspects of human health.
The growing availability of microbial genome sequences and advances in complementary …

Emerging science of the human microbiome

ML Jones, JG Ganopolsky, CJ Martoni, A Labbé… - Gut …, 2014 - Taylor & Francis
The human gastrointestinal tract hosts a large number of microbial cells which exceed their
mammalian counterparts by approximately 3-fold. The genes expressed by these …

Gut microbiota developments with emphasis on inflammatory bowel disease: report from the gut microbiota for health world summit 2016

H Eppinga, GM Fuhler, MP Peppelenbosch… - …, 2016 - gastrojournal.org
In the past decades the view of the gut microbiota has transformed from fighting the bad
bugs with antibiotics to protecting the good bugs that function as a defense barrier and …

The gut microbiome in health and disease: Inflammatory bowel diseases

S El-Sahhar, P Varga-Weisz - Advances in Ecological Research, 2022 - Elsevier
In the era of high throughput DNA sequencing technologies, there has been an explosion in
the last 10 years of our knowledge of human microbiomes, especially the gut microbiome …