Working against time: rapid radiotracer synthesis and imaging the human brain

JS Fowler, AP Wolf - Accounts of Chemical Research, 1997 - ACS Publications
Over 60 years ago, Lauritsen and Crane discovered carbon-11, a new radioactive isotope
which has a 20.4 min halflife and decays by positron emission. Since this preceded the …

Strategy for creating accurate functional imaging with PET and its relevance to SPECT

T Jones - Tomography in nuclear medicine. Proceedings of an …, 1996 - inis.iaea.org
[en] The unique role of positron emission tomography (PET) is discussed with respect to its
specificity and sensitivity for measuring, through quantitative imaging, molecular pathways …

[PDF][PDF] PET instrumentation, modelling and clinical application

H Herzog - ION AND SLOW POSITRON BEAM UTILISATION, 1999 - oecdnea.org
Positron emission tomography (PET) is a diagnostic imaging method to investigate
physiological and metabolic functions and their disorders in vivo. Dedicated ring systems of …

Fluorine-18 Labeling of Radiopharmaceuticals for PET Studies: Main Aspects and Problems Encountered in Chemical Syntheses

C Lemaire - Chemists' Views of Imaging Centers, 1995 - Springer
Positron emission tomography has considerably developed during the past ten years and
has proved to be the only original quantitative method appropriate to the study of the in vivo …

Functional imaging of physiological processes by positron emission tomography

G Westera, PA Schubiger - Physiology, 2003 - journals.physiology.org
Tracer technology makes it possible to observe physiological and biochemical processes in
the living organism in a dynamic mode. Positron emission tomography adds the use of …

Methods and instrumentation for positron emission tomography

MA Mandelkern, ME Phelps - Diagnostic nuclear medicine. Second …, 1988 - inis.iaea.org
[en] This paper reports on positron emission tomography (PET), a technique for the
noninvasive measurement of local tissue concentrations of injected radioactive tracers …

Short-lived positron emitter labeled radiotracers-present status

JS Fowler, AP Wolf - 1982 - osti.gov
The preparation of labelled compounds is important for the application of positron emission
transaxial tomography (PETT) in biomedical sciences. This paper describes problems and …

[引用][C] Positron emission tomography: Progress in brain imaging

ME Raichle - Nature, 1985 - nature.com
MoRE than a decade has passed since the introduction of positron emission tomo-graphy
(PET), a technique than can be used safely to measure physiological and biochemical …

[引用][C] Positron emission tomography of the central nervous system

DA Rottenberg, AJL Cooper - Trends in Biochemical Sciences, 1981 - Elsevier
Positron emission tomography (PET) is a computerized imaging technique which may
enable quantitative regional information about brain function to be obtained in vivo. In …

Radiopharmaceutical chemistry for positron emission tomography

Z Li, PS Conti - Advanced drug delivery reviews, 2010 - Elsevier
Molecular imaging is an emerging technology that allows the visualization of interactions
between molecular probes and biological targets. Molecules that either direct or are subject …