Environmental enrichment protects against stress-induced anxiety: Role of glucocorticoid receptor, ERK, and CREB signaling in the basolateral amygdala
LS Novaes, NB Dos Santos, RFP Batalhote… - …, 2017 - Elsevier
Environmental enrichment (EE) is an experimental animal model that enhances an animal's
opportunity to interact with sensory, motor, and social stimuli, compared to standard …
opportunity to interact with sensory, motor, and social stimuli, compared to standard …
Environmental enrichment prevents acute restraint stress-induced anxiety-related behavior but not changes in basolateral amygdala spine density
LS Novaes, NB Dos Santos, JG Perfetto… - …, 2018 - Elsevier
Previous studies showed that acute restraint stress or transient elevation of glucocorticoid
(GC) stress hormones produces emergent changes in both anxiety behavior and dendritic …
(GC) stress hormones produces emergent changes in both anxiety behavior and dendritic …
Differential impact of stress and environmental enrichment on corticolimbic circuits
Stress exposure can produce profound changes in physiology and behavior that can impair
health and well-being. Of note, stress exposure is linked to anxiety disorders and depression …
health and well-being. Of note, stress exposure is linked to anxiety disorders and depression …
Therapeutic and protective effect of environmental enrichment against psychogenic and neurogenic stress
C Fox, Z Merali, C Harrison - Behavioural brain research, 2006 - Elsevier
Environmental enrichment (EE) has beneficial neurobiological, physiological and behavioral
effects. The purpose of the present paper is to review the animal research literature …
effects. The purpose of the present paper is to review the animal research literature …
Increase of glucocorticoid receptor expression after environmental enrichment: relations to spatial memory, exploration and anxiety-related behaviors
P Sampedro-Piquero, A Begega, JL Arias - Physiology & behavior, 2014 - Elsevier
Environmental enrichment (EE) produces a remarkable degree of structural and functional
plasticity in the hippocampus and possible mediators of these changes, such as …
plasticity in the hippocampus and possible mediators of these changes, such as …
The neurogenic effects of an enriched environment and its protection against the behavioral consequences of chronic mild stress persistent after enrichment cessation …
NM Vega-Rivera, L Ortiz-López… - Behavioural Brain …, 2016 - Elsevier
Because stress may underlie the presence of depressive episodes, strategies to produce
protection against or to reverse the effects of stress on neuroplasticity and behavior are …
protection against or to reverse the effects of stress on neuroplasticity and behavior are …
Short-term environmental enrichment is sufficient to counter stress-induced anxiety and associated structural and molecular plasticity in basolateral amygdala
Moderate levels of anxiety enable individual animals to cope with stressors through
avoidance, and could be an adaptive trait. However, repeated stress exacerbates anxiety to …
avoidance, and could be an adaptive trait. However, repeated stress exacerbates anxiety to …
Alteration of cingulate long-term plasticity and behavioral sensitization to inflammation by environmental enrichment
Exposure to an enriched environment (EE) has been shown to induce cortical plasticity.
Considerable amount of research is focused on the effects of EE in the hippocampus; …
Considerable amount of research is focused on the effects of EE in the hippocampus; …
The basolateral amygdala regulates adaptation to stress via β-adrenergic receptor-mediated reductions in phosphorylated extracellular signal-regulated kinase
NM Grissom, S Bhatnagar - Neuroscience, 2011 - Elsevier
The reactivity of physiological systems and behavior to psychological stress is reduced with
increasing familiarity with a repeated stressor. This reduced reactivity, termed habituation, is …
increasing familiarity with a repeated stressor. This reduced reactivity, termed habituation, is …
The anxiolytic effect of environmental enrichment is mediated via amygdalar CRF receptor type 1
Environmental enrichment (EE) is known to have an anxiolytic effect in several animal
models; however, the molecular mechanisms underlying these behavioral changes are not …
models; however, the molecular mechanisms underlying these behavioral changes are not …
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