Spinal cord ischemia: development of a model in the mouse

L Lang-Lazdunski, K Matsushita, L Hirt, C Waeber… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—Spinal cord ischemia with resulting paraplegia is a devastating
complication of thoracoabdominal aortic surgery. Experimental models of spinal cord …

Spinal cord ischemic injury: Development of a new model in the rat

GK Kanellopoulos, H Kato, CY Hsu, NT Kouchoukos - Stroke, 1997 - Am Heart Assoc
Background and Purpose Spinal cord ischemic injury (SCII) with resulting paralysis is a
major cause of morbidity after operations on the thoracic aorta. Since the vascular supply to …

Blood flow and vascular permeability during motor dysfunction in a rabbit model of spinal cord ischemia.

TP Jacobs, O Kempski, D McKinley, AJ Dutka… - Stroke, 1992 - Am Heart Assoc
Delayed deterioration of neurological function after central nervous system ischemia is a
well-documented clinical problem. The purpose of our study was to elucidate the role of …

Transient spinal ischemia in the rat: characterization of behavioral and histopathological consequences as a function of the duration of aortic occlusion

M Marsala, TL Yaksh - Journal of Cerebral Blood Flow & …, 1994 - journals.sagepub.com
To characterize the behavioral and histopathological changes that occur in spinal cord after
transient ischemia, reversible occlusion of the descending aorta was achieved in the …

Spinal cord blood flow and pathophysiological changes after transient spinal cord ischemia in cats

T Yamada, T Morimoto, H Nakase, H Hirabayashi… - …, 1998 - journals.lww.com
OBJECTIVE: The goal was to study the hemodynamics and regional pathophysiological
changes in the spinal cord after transient vascular occlusion in cats. METHODS: We …

Effect of proximal arterial perfusion pressure on function, spinal cord blood flow, and histopathologic changes after increasing intervals of aortic occlusion in the rat

Y Taira, M Marsala - Stroke, 1996 - Am Heart Assoc
Background and Purpose Cross-clamping of the thoracic aorta results in spinal cord
ischemia and prominent systemic hypertension. Using a rat model of transient spinal cord …

Experimental ischemia of the spinal cord: Histologic studies after anterior spinal artery occlusion

LC Fried, O Aparicio - Neurology, 1973 - AAN Enterprises
Materials and methods We collected spinal cords from 22 rhesus monkeys that had surgical
occlusion of a major spinal artery in the thoracolilmbar region. Ligation of the anterior spinal …

Animal model for investigation of spinal cord injury caused by aortic cross-clamping

AK Qayumi, MT Janusz, DM Lyster… - Journal of Investigative …, 1997 - Taylor & Francis
The objective of this experimental protocol was to design a large animal model that could
simulte the ischemic condition caused by aortic cross-clamping during the operation for …

A mouse model of ischemic spinal cord injury with delayed paralysis caused by aortic cross-clamping

H Awad, DP Ankeny, Z Guan, P Wei… - The Journal of the …, 2010 - pubs.asahq.org
Background Spinal cord ischemia and paralysis are devastating perioperative complications
that can accompany open or endovascular repair surgery for aortic aneurysms. Here, we …

Evolution of spinal cord injury in a porcine model of prolonged aortic occlusion

JC Papakostas, MI Matsagas, IK Toumpoulis… - Journal of Surgical …, 2006 - Elsevier
BACKGROUND: Spinal cord injury and subsequent paraplegia remains an unpredictable
and devastating complication of thoracoabdominal aortic surgery. The aim of this study was …