The process of post-translational covalent modification of proteins represents a transcription-
independent regulatory mechanism allowing rapid alteration of protein activity and function …

The posttranslational modification of histone and other chromatin proteins has a well
recognized but poorly defined role in the physiology of gene expression. With implications …

Post-translational modification of proteins by lysine acetylation plays important regulatory
roles in living cells. The budding yeast Saccharomyces cerevisiae is a widely used …

Histone modifications are key epigenetic regulatory features that have important roles in
many cellular events. Lysine methylations mark various sites on the tail and globular …

Lysine methylation is a common posttranslational modification (PTM) of histones that is
important for the epigenetic regulation of transcription and chromatin in eukaryotes …

Several protein lysine methyltransferases and demethylases have been identified to have
critical roles in histone modification. A large body of evidence has indicated that their …

Protein lysine malonylation is a recently identified post-translational modification (PTM),
which is evolutionarily conserved from bacteria to mammals. Although analysis of lysine …

Histone methylation is believed to play important roles in epigenetic memory in various
biological processes. However, questions like whether the methylation marks themselves …

Methylation of lysine residues of histones is associated with functionally distinct regions of
chromatin, and, therefore, is an important epigenetic mark. Over the past few years, several …

Post-translational modifications (PTMs) of transcription factors play a crucial role in
regulating metabolic homeostasis. These modifications include phosphorylation …