Amelioration of subglottic stenosis by antimicrobial peptide eluting endotracheal tubes
MR Aronson, A Mehta, RM Friedman… - Cellular and Molecular …, 2023 - Springer
Introduction Pediatric subglottic stenosis (SGS) results from prolonged intubation where scar
tissue leads to airway narrowing that requires invasive surgery. We have recently …
tissue leads to airway narrowing that requires invasive surgery. We have recently …
Drug‐Eluting Endotracheal Tubes for Preventing Bacterial Inflammation in Subglottic Stenosis
MR Aronson, S Ali Akbari Ghavimi… - The …, 2022 - Wiley Online Library
Objectives/Hypothesis Subglottic stenosis (SGS) results from dysregulated extracellular
matrix deposition by laryngotracheal fibroblasts causing scar tissue formation following …
matrix deposition by laryngotracheal fibroblasts causing scar tissue formation following …
Molecular analysis of idiopathic subglottic stenosis for Mycobacterium species
A Gelbard, NG Katsantonis, M Mizuta… - The …, 2017 - Wiley Online Library
Objectives/Hypothesis Idiopathic subglottic stenosis (iSGS) is an unexplained obstruction
involving the lower laryngeal and upper tracheal airway. Persistent mucosal inflammation is …
involving the lower laryngeal and upper tracheal airway. Persistent mucosal inflammation is …
Characterizing the T cell repertoire in the proximal airway in health and disease
Objectives Recent translational scientific efforts in subglottic stenosis (SGS) support a
disease model where epithelial alterations facilitate microbiome displacement, dysregulated …
disease model where epithelial alterations facilitate microbiome displacement, dysregulated …
Laryngotracheal microbiota in adult laryngotracheal stenosis
Laryngotracheal stenosis is an obstructive respiratory disease that leads to voicing
difficulties and dyspnea with potential life-threatening consequences. The majority of …
difficulties and dyspnea with potential life-threatening consequences. The majority of …
[HTML][HTML] RNA sequencing of idiopathic subglottic stenosis tissues uncovers putative profibrotic mechanisms and identifies a prognostic biomarker
C Zhang, S Wang, MC Moura, SY Eunhee… - The American Journal of …, 2022 - Elsevier
Idiopathic subglottic stenosis (iSGS) is a localized airway disease that almost exclusively
affects females. Understanding the molecular mechanisms involved may provide insights …
affects females. Understanding the molecular mechanisms involved may provide insights …
Expression and roles of antimicrobial peptides in innate defense of airway mucosa: potential implication in cystic fibrosis
R Geitani, CA Moubareck, Z Xu… - Frontiers in …, 2020 - frontiersin.org
The treatment of respiratory infections is associated with the dissemination of antibiotic
resistance in the community and clinical settings. Development of new antibiotics is …
resistance in the community and clinical settings. Development of new antibiotics is …
Persistent inflammation and nitric oxide dysregulation are transcriptomic blueprints of subglottic stenosis
HCB Nguyen, TN Chao, NA Cohen… - Frontiers in Immunology, 2021 - frontiersin.org
Subglottic stenosis (SGS) is a recurrent, obstructive, fibroinflammatory disease of the upper
airway resulting in severe dyspnea, dysphonia, as well as other potentially fatal …
airway resulting in severe dyspnea, dysphonia, as well as other potentially fatal …
The antimicrobial peptide S100A8/A9 produced by airway epithelium functions as a potent and direct regulator of macrophage phenotype and function
W Skronska-Wasek, S Durlanik, HQ Le… - European …, 2022 - Eur Respiratory Soc
Background Elevated counts of alveolar macrophages and attenuated phagocytic capacity
are associated with chronic obstructive pulmonary disease (COPD). Factors governing …
are associated with chronic obstructive pulmonary disease (COPD). Factors governing …
Gut microbiota-derived acetate attenuates lung injury induced by influenza infection via protecting airway tight junctions
L Hu, L Sun, C Yang, DW Zhang, YY Wei… - Journal of Translational …, 2024 - Springer
Background Gut microbiota (GM) have been implicated as important regulators of
gastrointestinal symptom which is commonly occurred along with respiratory influenza A …
gastrointestinal symptom which is commonly occurred along with respiratory influenza A …