DIPG-39. ONCOHISTONE H3. 3K27M-DRIVEN CREB5/ID1 AXIS DICTATES THE MALIGNANT CELL STATES OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

W Zhou, C Xu, Y Tang, C Pan, L Zhang, Q Xi - Neuro-Oncology, 2024 - ncbi.nlm.nih.gov
BACKGROUND Diffuse intrinsic pontine glioma (DIPG) is a highly aggressive pediatric
cancer characterized by the presence of H3K27M-oncohistones, which drive relentless …
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DIPG-50. INSIGHTS INTO TUMORIGENESIS OF DIFFUSE INTRINSIC PONTINE GLIOMA-ONCOHISTONE AND SIGNALING

Y Sun, K Yan, D Wang, W Zhou, Y Wang, C Xu… - Neuro …, 2023 - ncbi.nlm.nih.gov
Diffuse intrinsic pontine glioma (DIPG) is a rare and incurable pediatric brain cancer with
survival of less than one year. Understanding the tumorigenesis mechanisms of DIPG and …
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[PDF] springer.com

Histone tail analysis reveals H3K36me2 and H4K16ac as epigenetic signatures of diffuse intrinsic pontine glioma

S An, JM Camarillo, TYT Huang, D Li, JA Morris… - Journal of Experimental …, 2020 - Springer
Background Diffuse intrinsic pontine glioma (DIPG) is an aggressive pediatric brainstem
tumor. Most DIPGs harbor a histone H3 mutation, which alters histone post-translational …
被引用次数：22 相关文章 所有 18 个版本

Dipg-41. Identification of Birc5 as a Novel Therapeutic Target for Diffuse Intrinsic Pontine Glioma

M Li, J Wang, Y Sui, T Li, F Liu, L Zhang, W Jiang… - Neuro …, 2018 - ncbi.nlm.nih.gov
Abstract Diffuse Intrinsic Pontine Glioma (DIPG) remains to be a lethal type of pediatric brain
tumor to date, indicating an urgent need of finding novel therapeutic strategy. Through …
被引用次数：1 相关文章 所有 2 个版本

DIPG-72. CREATION, CHARACTERIZATION AND CATALOGUING NEXT-GENERATION DIPG PATIENT-DERIVED CANCER CELL LINES: THE DIPG C3 PROJECT

S Bhatia, T Quinn, KH Chow, J Vogelzang… - Neuro …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Preclinical studies of diffuse intrinsic pontine glioma (DIPG) have increased
significantly over the past 15 years due to the development of DIPG disease-specific tools …
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[PDF] oup.com

DIPG-29. Genomic landscape of diffuse intrinsic pontine glioma: an analysis of the DIPG-BATs cohort

P Bandopadhayay, NF Greenwald, J Wala… - Neuro …, 2017 - academic.oup.com
INTRODUCTION: Diffuse intrinsic pontine glioma (DIPG) remains a devastating and
incurable disease. The DIPG-BATs clinical trial incorporates diagnostic biopsy with …
被引用次数：1 相关文章 所有 7 个版本
[PDF] oup.com

DIPG-69. CHARACTERISTICS OF PATIENTS≥ 10 YEARS OF AGE WITH DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIPG …

C Erker, A Lane, B Chaney, NY Escorza… - Neuro …, 2018 - academic.oup.com
Diffuse intrinsic pontine gliomas (DIPG) are deadly childhood brainstem tumors that
comprise approximately half of all pediatric high-grade gliomas (HGG). Recurrent, clonal …
被引用次数：3 相关文章 所有 4 个版本
[PDF] oup.com

DIPG-59. UPREGULATION OF PRENATAL PONTINE ID1 SIGNALING IN DIPG

MK Harris, VN Yadav, S Stallard, R Woo… - Neuro …, 2020 - academic.oup.com
Abstract Diffuse Intrinsic Pontine Glioma (DIPG) is an incurable pediatric brain tumor.
Current standard of care has shown no improvements in survival. Here, we report our study …
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DIPG-05. Histone H3. 3 K27M impairs SER31 phosphorylation, resulting in chromosomal instability, loss of cell cycle checkpoint control, and tumor formation

C Day, A Langfald, F Grigore, S Fadness… - Neuro …, 2020 - ncbi.nlm.nih.gov
Diffuse midline gliomas with the H3. 3 K27M mutation are lethal brain tumors in children. H3
K27M causes global loss of Lys27 triple methylation (Lys27me3), inducing epigenetic …
被引用次数：1 相关文章 所有 2 个版本
[HTML] researchgate.net

[HTML][HTML] DIPG-48. DIPG THROUGH THE LOOKING GLASS

SS Senga - Neuro-Oncology, 2023 - researchgate.net
Diffuse intrinsic pontine glioma (DIPG) has a peculiar pathogenesis with canonical Histone
variants H3. 1/H3. 2 wherein Lysine 27 (H3K27) is substituted to methionine (H3K27M). It is …
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