The activating interplay of thrombosis and inflammation (thromboinflammation) has been
established as a major underlying pathway, driving not only cardiovascular disease but also …

Neutrophils and platelets are among the most abundant cell types in peripheral blood and
characterized by high plasticity and a readily available reservoir of surface proteins and …

Platelets are well characterized for their indispensable role in primary hemostasis to control
hemorrhage. Research over the past years has provided a substantial body of evidence …

Background: Neutrophil extracellular trap (NET) production has been implicated in the
pathogenesis of thromboinflammatory conditions such as Sickle Cell Disease (SCD) …

A state-of-the-art lecture titled “novel mechanisms of thrombo-inflammation during infection”
was presented at the ISTH Congress in 2022. Platelet, neutrophil, and endothelial cell …

Background: Atherosclerotic cardiovascular diseases are characterized by a dysregulated
inflammatory and thrombotic state, leading to devastating complications with increased …

Neutrophils and neutrophil extracellular traps (NETs) have a robust relationship with
atherothrombotic disease risk, which led to the idea that interfering with the release of NETs …

Platelets are increasingly being recognized for playing roles beyond thrombosis and
hemostasis. Today we know that they mediate inflammation by direct interactions with innate …

SARS-CoV-2 is a member of the family of coronaviruses associated with severe outbreaks of
respiratory diseases in recent decades and is the causative agent of the COVID-19 …

Thrombotic events, both arterial and venous, are a major health concern worldwide. Further,
autoimmune diseases, such as systemic lupus erythematosus, anti-neutrophil cytoplasmic …