Abstract Human enterovirus 71 (EV71) and Coxsackievirus A16 (CA16) are major causative
agents of hand, foot, and mouth disease (HFMD) especially in infants and children under 5 …

To complement traditional antivirals, natural compounds that act via host targets and present
high barriers to resistance are of increasing interest. In the work reported here, we detected …

A series of naturally occurring cardenolides that exhibit potent anti-transmissible
gastroenteritis virus (TGEV) activity in swine testicular (ST) cells has been identified. In an …

Porcine epidemic diarrhea virus (PEDV) causes high mortality in pigs. PEDV main protease
(Mpro) plays an essential role in viral replication. We solved the structure of PEDV Mpro …

Abstract Enterovirus 71 (EV71) is a major causative agent for hand, foot and mouth disease
(HFMD), and fatal neurological and systemic complications in children. However, there is …

Porcine epidemic diarrhea virus (PEDV), a member of the Coronaviridae family, causes
acute diarrhea, vomiting, dehydration, and high mortality rates in neonatal piglets. Severe …

Porcine epidemic diarrhea coronavirus (PEDV) has significantly damaged America's pork
industry. Here we investigate the receptor usage and cell entry of PEDV. PEDV recognizes …

Abstract Ethnopharmacological relevance Angelica dahurica (Hoffm.) Benth. & Hook. f. ex
Franch. & Sav.(Umbelliferae family) is an herbaceous, perennial plant native to northern and …

This research was aimed to evaluate the in vitro antiviral effect and the mechanism of the
effect of Peganum. harmala seeds extract against influenza A virus infection using Madin …

The aim of this study was to search for new antiviral agents from Chinese herbal medicine.
Pure flavonoids and aqueous extracts of Caesalpinia pulcherrima Swartz were used in …