Oral nanozyme-engineered probiotics for the treatment of ulcerative colitis
H Zhao, Y Du, L Liu, Y Du, K Cui, P Yu, L Li… - Journal of Materials …, 2022 - pubs.rsc.org
Probiotic-based therapy for ulcerative colitis (UC) is a novel and promising approach that
has gained much popularity in recent years. However, probiotics may be easily captured …
has gained much popularity in recent years. However, probiotics may be easily captured …
Nanoprobiotics for remolding the pro-inflammatory microenvironment and microbiome in the treatment of colitis
J Li, M Sun, L Liu, W Yang, A Sun, J Yu, D Liu… - Nano Letters, 2023 - ACS Publications
Despite the great progress of current bacterially based biotherapeutics, their unsatisfying
efficacy and underlying safety problems have limited their clinical application. Herein …
efficacy and underlying safety problems have limited their clinical application. Herein …
Probiotic‐inspired nanomedicine restores intestinal homeostasis in colitis by regulating redox balance, immune responses, and the Gut Microbiome
Microbiota‐based therapeutics offer innovative strategies to treat inflammatory bowel
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …
A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease
F Zeng, Y Shi, C Wu, J Liang, Q Zhong, K Briley… - Journal of …, 2022 - Springer
Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …
Construction of pH‐Dependent Nanozymes with Oxygen Vacancies as the High‐Efficient Reactive Oxygen Species Scavenger for Oral‐Administrated Anti …
N Zhao, FE Yang, CY Zhao, SW Lv… - Advanced …, 2021 - Wiley Online Library
It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
Gastrointestinal Microenvironment Responsive Nanoencapsulation of Probiotics and Drugs for Synergistic Therapy of Intestinal Diseases
P Peng, T Feng, X Yang, C Nie, L Yu, R Ding, Q Zhou… - ACS …, 2023 - ACS Publications
The gut microbiota are prominent in preserving intestinal environmental homeostasis and
managing human health, and their dysbiosis has been directly related to many kinds of …
managing human health, and their dysbiosis has been directly related to many kinds of …
Macrophage-biomimetic liposomes delivery of carbon dots nanozymes ameliorate ulcerative colitis by modulating inflammation pathways and remodeling the redox …
Y Ma, J Zhao, Z Deng, B Gao, C Xu, X Yan… - Chemical Engineering …, 2023 - Elsevier
As a recurrent chronic inflammatory intestinal disease, ulcerative colitis (UC) has seriously
affected the life quality of patients. Numerous studies have demonstrated excessive reactive …
affected the life quality of patients. Numerous studies have demonstrated excessive reactive …
Nanozyme-enhanced probiotic spores regulate the intestinal microenvironment for targeted acute gastroenteritis therapy
Antibiotic therapeutics to combat intestinal pathogen infections often exacerbate microbiota
dysbiosis and impair mucosal barrier functions. Probiotics are promising strategies, because …
dysbiosis and impair mucosal barrier functions. Probiotics are promising strategies, because …
Rational design of orally administered cascade nanozyme for inflammatory bowel disease therapy
Y Yu, X Zhao, X Xu, C Cai, X Tang, Q Zhang… - Advanced …, 2023 - Wiley Online Library
Inflammatory bowel disease (IBD) affects millions of individuals worldwide annually. Enteric
reactive oxygen species (ROS) play critical roles in the physiology and pathology of IBD …
reactive oxygen species (ROS) play critical roles in the physiology and pathology of IBD …
Probiotics Armed with In Situ Mineralized Nanocatalysts and Targeted Biocoatings for Multipronged Treatment of Inflammatory Bowel Disease
T Chen, W Meng, Y Li, X Li, X Yu, J Qi, D Ding… - Nano Letters, 2024 - ACS Publications
While oral probiotics show promise in treating inflammatory bowel disease, the primary
challenge lies in sustaining their activity and retention within the inflamed gastrointestinal …
challenge lies in sustaining their activity and retention within the inflamed gastrointestinal …