Bevacizumab-induced hypertension: pathogenesis and management
KN Syrigos, E Karapanagiotou, P Boura, C Manegold… - BioDrugs, 2011 - Springer
Bevacizumab, a recombinant humanized monoclonal antibody targeting the vascular
endothelial growth factor (VEGF), has been approved in the US as first-and second-line …
endothelial growth factor (VEGF), has been approved in the US as first-and second-line …
Analysis of early hypertension and clinical outcome with bevacizumab: results from seven phase III studies
HI Hurwitz, PS Douglas, JP Middleton… - The …, 2013 - academic.oup.com
Background. Hypertension is associated with antivascular endothelial growth factor
treatment, but the clinical implications of hypertension are uncertain. To assess the …
treatment, but the clinical implications of hypertension are uncertain. To assess the …
Retrospective analysis of bevacizumab‐induced hypertension and clinical outcome in patients with colorectal cancer and lung cancer
A Nakaya, T Kurata, T Yokoi, S Iwamoto… - Cancer …, 2016 - Wiley Online Library
Bevacizumab (Avastin®), a humanized therapeutic monoclonal antibody that targets
vascular endothelial growth factor, is widely used in cancer treatment. Patients who are …
vascular endothelial growth factor, is widely used in cancer treatment. Patients who are …
An observational study of bevacizumab‐induced hypertension as a clinical biomarker of antitumor activity
O Mir, R Coriat, L Cabanes, S Ropert… - The …, 2011 - academic.oup.com
Background. Hypertension is a common toxicity of bevacizumab, but the frequency of
assessment of blood pressure and standardized grading remain to be defined. This study …
assessment of blood pressure and standardized grading remain to be defined. This study …
Bevacizumab-induced hypertension: Clinical presentation and molecular understanding
M Li, DL Kroetz - Pharmacology & therapeutics, 2018 - Elsevier
Bevacizumab is a vascular endothelial growth factor-A-specific angiogenesis inhibitor
indicated as an adjunct to chemotherapy for the treatment of several types of cancer …
indicated as an adjunct to chemotherapy for the treatment of several types of cancer …
Increased risk of high-grade hypertension with bevacizumab in cancer patients: a meta-analysis
V Ranpura, B Pulipati, D Chu, X Zhu… - American journal of …, 2010 - academic.oup.com
Background Hypertension is associated with the use of bevacizumab, an angiogenesis
inhibitor widely used in cancer therapy. Currently, the risk of severe hypertension associated …
inhibitor widely used in cancer therapy. Currently, the risk of severe hypertension associated …
[引用][C] Angiogenesis inhibitors and hypertension: an emerging issue
DA Sica - Journal of Clinical Oncology, 2006 - ascopubs.org
Any of a number of therapeutic agents or chemical substances can induce transient or more
long-lasting forms of hypertension. Drugs that cause hypertension do so by either …
long-lasting forms of hypertension. Drugs that cause hypertension do so by either …
Evaluation of hypertension as a marker of bevacizumab efficacy
R Ryanne Wu, PA Lindenberg, R Slack… - Journal of …, 2009 - Springer
Background Predictive factors for efficacy of vascular endothelial growth factor pathway-
targeted therapies have not been identified or confirmed. Hypertension has been observed …
targeted therapies have not been identified or confirmed. Hypertension has been observed …
Analysis of early hypertension (HTN) and clinical outcome with bevacizumab (BV).
H Hurwitz, PS Douglas, JP Middleton… - Journal of Clinical …, 2010 - ascopubs.org
3039 Background: HTN is associated with anti-VEGF treatment (Tx), but this association has
not been well studied. To assess the prognostic and predictive importance of BV-related …
not been well studied. To assess the prognostic and predictive importance of BV-related …
[HTML][HTML] Blood pressure as a potential biomarker of the efficacy angiogenesis inhibitor
BI Levy - Annals of oncology, 2009 - annalsofoncology.org
Arterial hypertension is a commonly reported side-effect in all clinical trials testing all
inhibitors of angiogenesis and especially inhibitors of vascular endothelial growth factor …
inhibitors of angiogenesis and especially inhibitors of vascular endothelial growth factor …