The different cell types comprising cardiac muscle express one or more of the three isoforms
(neuronal NOS, or nNOS; inducible NOS, or iNOS; and endothelial NOS, or eNOS) of nitric …

Nitric oxide (NO) produced in the heart by nitric oxide synthase (NOS) is a highly reactive
signaling molecule and an important modulator of myocardial function. NOS catalyzes the …

Recognition of significance of nitric oxide synthases (NOS) in cardiovascular regulations has
led to intensive research and development of therapies focused on NOS as potential …

Nitric oxide (NO) is produced from virtually all cell types composing the myocardium and
regulates cardiac function through both vascular-dependent and-independent effects. The …

Nitric oxide, which is produced endogenously within cardiac myocytes by three distinct
isoforms of nitric oxide synthase, is a key regulator of myocardial function. This review will …

The mammalian heart expresses all three isoforms of nitric oxide synthases (NOS) in diverse
cell types of the myocardium. Despite their apparent promiscuity, the NOS isoforms support …

Nitric oxide (NO) has been shown to regulate cardiac function, both in physiological
conditions and in disease states. However, several aspects of NO signalling in the …

Emerging evidence shows that neuronal nitric oxide synthase (nNOS) plays several
diverging roles in modulating cardiac function. This review examines the nitric oxide (NO) …

Nitric oxide synthases (NOS) are the enzymes responsible for nitric oxide (NO) generation.
To date, 3 distinct NOS isoforms have been identified: neuronal NOS (NOS1), inducible NOS …

Recent report suggest that endothelial-dependent relaxant factor, recoggnized as nitric
oxide (NO), reduces myocardial contractility. Here, we showed that both exposures to …