The concept of platelets as important players in the process of atherogenesis has become
increasingly accepted due to accumulating experimental and clinical evidence. Despite the …

It is now clear that the monocyte/macrophage has a crucial role in the development of
atherosclerosis. This cell appears to be involved in all stages of atherosclerotic plaque …

Atherosclerosis, the cause of myocardial infarction, stroke, and ischemic gangrene, is an
inflammatory disease. The atherosclerotic process is initiated when cholesterol-containing …

Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress
and endothelial dysfunction. Oxidation of low-density lipoprotein (LDL) cholesterol is one of …

It is now widely accepted that the development of atherosclerotic lesions involves a chronic
inflammatory response that includes both innate and adaptive immune mechanisms …

Atherosclerosis is currently the leading factor of death in developed countries. It is now
recognized as a chronic immune-inflammatory disease, whose initial stages involve the …

Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …

Recent studies have highlighted the role of inflammatory mediators and the cells of the
innate and adaptive immune response in the initiation, growth and rupture of atherosclerotic …

Despite marked advances in medical research over the past several decades,
cardiovascular disease continues to be the primary cause of morbidity and mortality …

Atherosclerosis is no longer considered a disorder due to abnormalities in lipid metabolism.
In fact, the inciting event of atherosclerosis is likely an inflammatory insult that occurs …