[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

Cytokines in atherosclerosis: pathogenic and regulatory pathways

A Tedgui, Z Mallat - Physiological reviews, 2006 - journals.physiology.org
Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

Recent advances on the role of cytokines in atherosclerosis

H Ait-Oufella, S Taleb, Z Mallat… - … , thrombosis, and vascular …, 2011 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disease of the arterial wall driven by innate and
adaptive immune responses. Inflammation controls the development and the destabilization …

Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets

JWE Moss, DP Ramji - Future medicinal chemistry, 2016 - Taylor & Francis
Atherosclerosis, the primary cause of cardiovascular disease (CVD), is a chronic
inflammatory disorder in the walls of medium and large arteries. CVD is currently …

Inflammatory cytokines in atherosclerosis: current therapeutic approaches

D Tousoulis, E Oikonomou, EK Economou… - European heart …, 2016 - academic.oup.com
The notion of atherosclerosis as a chronic inflammatory disease has intensified research on
the role of cytokines and the way these molecules act and interact to initiate and sustain …

Cytokines regulate vascular functions related to stability of the atherosclerotic plaque

P Libby, G Sukhova, RT Lee… - Journal of cardiovascular …, 1995 - journals.lww.com
The cytokines are multipotent mediators of inflammation and immunity that can affect key
functions of vascular wall cells. Growing evidence suggests that cytokines participate as …

The role of cytokines in the development of atherosclerosis

AR Fatkhullina, IO Peshkova, EK Koltsova - Biochemistry (Moscow), 2016 - Springer
Atherosclerosis contributes to the development of many cardiovascular diseases, which
remain the leading cause of death in developed countries. Atherosclerosis is a chronic …

Cytokines and atherosclerosis: a comprehensive review of studies in mice

R Kleemann, S Zadelaar, T Kooistra - Cardiovascular research, 2008 - academic.oup.com
In the past few years, inflammation has emerged as a major driving force of atherosclerotic
lesion development. It is now well-established that from early lesion to vulnerable plaque …

Cytokines as therapeutic targets for cardio-and cerebrovascular diseases

L Liberale, S Ministrini, F Carbone, GG Camici… - Basic Research in …, 2021 - Springer
Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic
complications still account for substantial morbidity and mortality worldwide. In this context …

Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition

A Munjal, R Khandia - Advances in protein chemistry and structural biology, 2020 - Elsevier
The term atherosclerosis refers to the condition of deposition of lipids and other substances
in and on the artery walls, called as plaque that restricts the normal blood flow. The plaque …