[HTML][HTML] Neuronal reprogramming in treating spinal cord injury

X Chen, H Li - Neural regeneration research, 2022 - journals.lww.com
Spinal cord injury represents a devastating central nervous system injury that could impair
the mobility and sensory function of afflicted patients. The hallmarks of spinal cord injury …

[HTML][HTML] Spinal cord injury and related clinical trials

YH Kim, KY Ha, SI Kim - Clinics in orthopedic surgery, 2017 - synapse.koreamed.org
Spinal cord injury (SCI) has been considered an incurable condition and it often causes
devastating sequelae. In terms of the pathophysiology of SCI, reducing secondary damage …

Regenerative therapies for spinal cord injury

N Ashammakhi, HJ Kim, A Ehsanipour… - … Engineering Part B …, 2019 - liebertpub.com
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …

[HTML][HTML] Stem cells therapy for spinal cord injury: an overview of clinical trials

S Silvestro, P Bramanti, O Trubiani… - International Journal of …, 2020 - mdpi.com
Spinal cord injury (SCI) is a traumatic lesion that causes disability with temporary or
permanent sensory and/or motor deficits. The pharmacological approach still in use for the …

Electrical stimulation as a tool to promote plasticity of the injured spinal cord

AS Jack, C Hurd, J Martin, K Fouad - Journal of Neurotrauma, 2020 - liebertpub.com
Unlike their peripheral nervous system counterparts, the capacity of central nervous system
neurons and axons for regeneration after injury is minimal. Although a myriad of therapies …

Recent advances in pathophysiology and treatment of spinal cord injury

CE Hulsebosch - Advances in physiology education, 2002 - journals.physiology.org
Thirty years ago, patients with spinal cord injury (SCI) and their families were told “nothing
can be done” to improve function. Since the SCI patient population is reaching normal life …

Recent therapeutic strategies for spinal cord injury treatment: possible role of stem cells

D Garbossa, M Boido, M Fontanella, C Fronda… - Neurosurgical …, 2012 - Springer
Spinal cord injury (SCI) often results in significant dysfunction and disability. A series of
treatments have been proposed to prevent and overcome the formation of the glial scar and …

Concise review: Spinal cord injuries: how could adult mesenchymal and neural crest stem cells take up the challenge?

V Neirinckx, D Cantinieaux, C Coste, B Rogister… - Stem …, 2014 - academic.oup.com
Since several years, adult/perinatal mesenchymal and neural crest stem cells have been
widely used to help experimental animal to recover from spinal cord injury. More …

[HTML][HTML] Filling the gap: neural stem cells as a promising therapy for spinal cord injury

IM Pereira, A Marote, AJ Salgado, NA Silva - Pharmaceuticals, 2019 - mdpi.com
Spinal cord injury (SCI) can lead to severe motor, sensory and social impairments having a
huge impact on patients' lives. The complex and time-dependent SCI pathophysiology has …

[HTML][HTML] Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements

RM Dorrian, CF Berryman, A Lauto… - Frontiers in Cellular …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …