[HTML][HTML] Mesenchymal stem cell therapy in traumatic spinal cord injury: a systematic review

R Montoto-Meijide, R Meijide-Faílde… - International Journal of …, 2023 - mdpi.com
Recovery from a traumatic spinal cord injury (TSCI) is challenging due to the limited
regenerative capacity of the central nervous system to restore cells, myelin, and neural …

Regenerative rehabilitation with conductive biomaterials for spinal cord injury

EA Kiyotake, MD Martin, MS Detamore - Acta biomaterialia, 2022 - Elsevier
The individual approaches of regenerative medicine efforts alone and rehabilitation efforts
alone have not yet fully restored function after severe spinal cord injury (SCI). Regenerative …

[HTML][HTML] Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury

N Hejrati, MG Fehlings - Current Opinion in Pharmacology, 2021 - Elsevier
Traumatic spinal cord injuries (SCIs) have far-reaching physical, social, and financial
consequences. While medical advancements have improved supportive therapeutic …

Advances in electrical and magnetic stimulation on nerve regeneration

Y Qian, Y Cheng, J Cai, X Zhao, Y Ouyang… - Regenerative …, 2019 - Taylor & Francis
Central and peripheral nerve injuries pose a great threat to people. Complications such as
inflammation, muscle atrophy, traumatic neuromas and delayed reinnervation can bring …

The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury

CS Ahuja, A Mothe, M Khazaei… - Stem cells …, 2020 - academic.oup.com
Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …

Neural stem cell-conditioned medium suppresses inflammation and promotes spinal cord injury recovery

Z Cheng, DB Bosco, L Sun, X Chen, Y Xu… - Cell …, 2017 - journals.sagepub.com
Spinal cord injury (SCI) causes functional impairment as a result of the initial injury followed
by secondary injury mechanism. SCI provokes an inflammatory response that causes …

Clinical translation of stem cell based interventions for spinal cord injury—Are we there yet?

HS Chhabra, K Sarda - Advanced Drug Delivery Reviews, 2017 - Elsevier
Recent advances in basic science in research related to spinal cord injury (SCI) and
regeneration have led to a variety of novel experimental therapeutics designed to promote …

Electrospun fibers for spinal cord injury research and regeneration

NJ Schaub, CD Johnson, B Cooper… - Journal of …, 2016 - liebertpub.com
Electrospinning is the process by which a scaffold containing micrometer and nanometer
diameter fibers are drawn from a polymer solution or melt using a large voltage gradient …

[HTML][HTML] Crosstalk between stem cell and spinal cord injury: pathophysiology and treatment strategies

A Shao, S Tu, J Lu, J Zhang - Stem cell research & therapy, 2019 - Springer
The injured spinal cord is difficult to repair and regenerate. Traditional treatments are not
effective. Stem cells are a type of cells that have the potential to differentiate into various …