Targeted therapies using electrical and magnetic neural stimulation for the treatment of chronic pain in spinal cord injury
Background Chronic neuropathic pain is one of the most common and disabling symptoms
in individuals with spinal cord injury (SCI). Over two-thirds of subjects with SCI suffer from …
in individuals with spinal cord injury (SCI). Over two-thirds of subjects with SCI suffer from …
Spinal cord injuries: how could cell therapy help?
A Badner, AM Siddiqui, MG Fehlings - Expert opinion on biological …, 2017 - Taylor & Francis
Introduction: Spinal cord injury (SCI) is a devastating condition, where regenerative failure
and cell loss lead to paralysis. The heterogeneous and time-sensitive pathophysiology has …
and cell loss lead to paralysis. The heterogeneous and time-sensitive pathophysiology has …
Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury
M Abematsu, K Tsujimura, M Yamano… - The Journal of …, 2010 - Am Soc Clin Investig
The body's capacity to restore damaged neural networks in the injured CNS is severely
limited. Although various treatment regimens can partially alleviate spinal cord injury (SCI) …
limited. Although various treatment regimens can partially alleviate spinal cord injury (SCI) …
Neural stem cells: promoting axonal regeneration and spinal cord connectivity
Spinal cord injury (SCI) leads to irreversible functional impairment caused by neuronal loss
and the disruption of neuronal connections across the injury site. While several experimental …
and the disruption of neuronal connections across the injury site. While several experimental …
The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration
TH Hutson, S Di Giovanni - Nature Reviews Neurology, 2019 - nature.com
Over the past decade, we have witnessed a flourishing of novel strategies to enhance
neuroplasticity and promote axon regeneration following spinal cord injury, and results from …
neuroplasticity and promote axon regeneration following spinal cord injury, and results from …
Clinical study of NeuroRegen scaffold combined with human mesenchymal stem cells for the repair of chronic complete spinal cord injury
Y Zhao, F Tang, Z Xiao, G Han, N Wang… - Cell …, 2017 - journals.sagepub.com
Regeneration of damaged neurons and recovery of sensation and motor function after
complete spinal cord injury (SCI) are challenging. We previously developed a collagen …
complete spinal cord injury (SCI) are challenging. We previously developed a collagen …
Transplantation of cerebral dopamine neurotrophic factor transducted BMSCs in contusion spinal cord injury of rats: promotion of nerve regeneration by alleviating …
H Zhao, L Cheng, X Du, Y Hou, Y Liu, Z Cui… - Molecular neurobiology, 2016 - Springer
Traumatic spinal cord injury (SCI) causes neuron death and axonal damage resulting in
functional motor and sensory loss, showing limited regeneration because of adverse …
functional motor and sensory loss, showing limited regeneration because of adverse …
Rehabilitation technologies and interventions for individuals with spinal cord injury: translational potential of current trends
KE Musselman, M Shah, J Zariffa - Journal of neuroengineering and …, 2018 - Springer
In the past, neurorehabilitation for individuals with neurological damage, such as spinal cord
injury (SCI), was focused on learning compensatory movements to regain function …
injury (SCI), was focused on learning compensatory movements to regain function …
Combination of multifaceted strategies to maximize the therapeutic benefits of neural stem cell transplantation for spinal cord repair
DH Hwang, HM Kim, YM Kang, IS Joo… - Cell …, 2011 - journals.sagepub.com
Neural stem cells (NSCs) possess therapeutic potentials to reverse complex pathological
processes following spinal cord injury (SCI), but many obstacles remain that could not be …
processes following spinal cord injury (SCI), but many obstacles remain that could not be …
Cell transplantation therapy for spinal cord injury
Spinal cord injury can lead to severe motor, sensory and autonomic dysfunction. Currently,
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …