The induction of inflammatory cytokines during respiratory viral infections contributes to both
disease pathogenesis and resolution. The present studies investigated the role of the …

Rationale: Patients who developed acute respiratory distress syndrome (ARDS) after
infection with severe respiratory viruses (eg, severe acute respiratory syndrome …

Rationale: The B cell–attracting chemokine CXCL13 is an important mediator in the
formation of tertiary lymphoid organs (TLOs). Increased numbers of ectopic lymphoid …

Rationale: After lung transplantation, insults to the allograft generally result in one of four
histopathologic patterns of injury:(1) acute rejection,(2) lymphocytic bronchiolitis,(3) …

The lung is continuously exposed to bacteria and their products, and has developed a
complex defense mechanism, including neutrophil recruitment. In mice, keratinocyte cell …

The role of chemokines in chronic inflammatory responses are central to the recruitment of
particular subsets of leukocytes. In the present studies, we have examined the role of CCR1 …

CXCR2/IL-8RB was the only receptor previously reported in mice for ELR+ CXC
chemokines, whereas the receptors for these chemokines in human include both CXCR1 …

Chronic obstructive pulmonary disease (COPD) patients exhibit chronic inflammation, both
in the lung parenchyma and the airways, which is characterised by an increased infiltration …

Chemokines are a superfamily of chemotactic cytokines that direct the movement of cells
throughout the body under homeostatic and inflammatory conditions. The mucosal …

Convincing correlates of protective immunity against tuberculosis have been elusive. In
BALB/c mice, intranasal immunization with a replication-deficient recombinant adenovirus …