Overview: antifungal combination therapy.

AM Sugar - Current Opinion in Investigational Drugs (London …, 2001 - europepmc.org
We have yet to realize the clinical benefits of combination antifungal therapy, but the
literature is beginning to show the potential positive and negative aspects of this approach …

Combinational antifungal therapy and recent trends in drug discovery

I Ahmad, MSA Khan, M Zahin, M Owais… - … Infections: Problems and …, 2010 - Springer
Invasive fungal infections are a major problem in immunocompromised patients. This has
necessitated an increased interest in the development of new antifungals to treat these life …

Decision making in antifungal monotherapy versus combination therapy

RE Lewis - … : The Journal of Human Pharmacology and Drug …, 2006 - Wiley Online Library
The availability of new antifungal agents with novel mechanisms of action and improved
tolerability has widened the possibilities for combination therapy for difficult‐to‐treat …

Considerations in clinical trials of combination antifungal therapy

JH Powers - Clinical infectious diseases, 2004 - academic.oup.com
The cure rate for serious fungal diseases with currently available agents used as
monotherapy is not optimal. The introduction of new classes of antifungal drugs in the last …

Combination antifungal therapy: the new frontier

JA Vazquez - Future Microbiology, 2007 - Taylor & Francis
The past decade has seen a significant increase in the incidence of invasive fungal
infections. The antifungal armamentarium for the treatment of serious fungal infections …

Combination antifungal therapy

MD Johnson, C MacDougall… - Antimicrobial agents …, 2004 - Am Soc Microbiol
The availability of new antifungal agents with novel mechanisms of action has stimulated
renewed interest in combination antifungal therapies. In particular, and despite the limited …

Toward more effective antifungal therapy: the prospects of combination therapy

DP Kontoyiannis, RE Lewis - British journal of haematology, 2004 - Wiley Online Library
The availability of new antifungal agents with unique mechanisms of action and improved
tolerability has widened the possibilities for the use of combination antifungal therapy for …

Combination antifungal therapy: A strategy for the management of invasive fungal infections

AJ Carrillo Muñoz, JL Finquelievich, C Tur Tur, E Eraso… - 2014 - repositorio.unne.edu.ar
Invasive mycoses have become an important public health problem as their incidence has
increased dramatically in the last decades, while the discovery of the ideal antifungal agent …

Synergy against fungal pathogens: working together is better than working alone

R Musiol, A Mrozek-Wilczkiewicz… - Current medicinal …, 2014 - ingentaconnect.com
Opportunistic fungi are the most important pathogens in modern world. They are responsible
for severe infections in majority of immunocompromised patients. These microorganisms are …

Antifungal therapy.

BD Pauw - 2011 - cabidigitallibrary.org
The management of fungal diseases is challenging. In fact, a number of difficulties have
limited the reliability of the results obtained in clinical studies to date. This article discussed …