Partially reduced heterocyclic compounds such as 1, 4, 5, 6-tetrahydropyrimidines are often
found to possess interesting pharmacological properties. Yet, the synthetic routes towards …

The three-component Biginelli reaction for the synthesis of dihydropyrimidinone and
corresponding dihydropyrimidinethiones (DHPMs) has been known for more than a century …

We report the development of a novel three-component coupling reaction (3CC) for the
synthesis of alkoxy tetrahydropyridopyrimidines. Systematic optimization of reaction …

Background: In synthetic and medicinal chemistry, multi-component reactions (MCRs) are
considered an essential tool in synthesizing bioactive heterocyclic scaffolds. These …

An efficient one-pot synthesis of novel N-substituted 1, 4-dihydropyridine derivatives via a
three-component reaction of primary amines, dialkyl acetylenedicarboxylates, and methyl …

Synthesis of 2,6-Dialkyl-1,2,5,6-Tetrahydropyridines and Their Applications in Total Synthesis
Page 1 Current Organic Synthesis, 2004, 1, 83-109 83 1570-1794/04 $45.00+.00 © 2004 …

A novel four-component diastereoselective synthesis of polysubstituted tetrahydropyridines
is reported. The Michael addition–Mannich reaction–cyclization–dehydration cascade of …

A regioselective synthesis of 2, 6-diarylpyridines through base (sodium hydroxide in DMSO)
catalyzed ring transformation of suitably functionalized 2H-pyran-2-ones with benzamide …

Two highly efficient, green protocols have been developed for the synthesis of 3, 4-
dihydropyridin-2-one derivatives from different starting materials exploring two reaction …

The multicomponent green methodologies are an ideal instrument in organic synthesis.
Environmentally benign, facile, and efficient multicomponent synthesis of [(2 H‐pyran‐3 …