One-pot synthesis of 3, 4-dihydropyridin-2-one via Michael addition of in situ–generated enaminones

JB Senthil Kumar, N Kumari… - Synthetic Communications, 2013 - Taylor & Francis
Herein we have reported a facile solvent-, catalyst-, and aldehyde-free, one-pot synthesis of
3, 4-dihydropyridin-2-one from 1, 3-diones using simple and mild reaction conditions. The …

An efficient organocatalytic method for tandem synthesis of functionalized 2-pyridones

I Yavari, MJ Bayat - Tetrahedron letters, 2011 - Elsevier
An efficient organocatalytic method for tandem synthesis of functionalized 2-pyridones -
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Highly Efficient Reusable Carboxy Group Functionalized Imidazolium Salts for a Simple and Cost-effective Preparation of pyrano [2, 3-d] pyrimidinone Derivatives

E Ezzatzadeh… - … Chemistry & High …, 2021 - ingentaconnect.com
Aims and Objective: In the current study, environmentally benign and cost-effective
procedures were suggested for the preparation of carboxy group functionalized imidazolium …

Comprehensive Overview of Progress in Functionalization of 2‐Pyridone and 2, 4‐Dihydroxy Pyridine: Key Constituents of Vital Natural Products

N Yadav, S Sangwan, R Kumar, S Chauhan… - …, 2021 - Wiley Online Library
Nitrogen heterocycles have found a key role in biologically active natural products.
Pyridones, specifically 2‐pyridone and 2, 4‐dihydoxypyridine are an extensive class of …

Anti‐Proliferative 1, 4‐Dihydropyridine and Pyridine Derivatives Synthesized through a Catalyst‐Free, One‐Pot Multi‐Component Reaction

MG Sharma, RM Vala, DM Patel, I Lagunes… - …, 2018 - Wiley Online Library
In this study, we explored the catalyst‐free one‐pot multi‐component synthesis of 1, 4‐
dihydropyridine derivatives by following green chemistry protocol. The present approach …

Efficient and facile 'on-solvent' multicomponent synthesis of medicinally privileged pyrano[3,2-c]pyridine scaffold

MN Elinson, FV Ryzhkov, AN Vereshchagin… - Research on Chemical …, 2018 - Springer
The new type of 'on-solvent'multicomponent reaction was found: transformation of
benzaldehydes, malononitrile and 4–hydroxy-6-methylpyridin-2 (1 H)-one in the presence of …

A facile strategy for the one pot multicomponent synthesis of spiro dihydropyridines from amines and activated alkynes

SE Kiruthika, NV Lakshmi, BR Banu, PT Perumal - Tetrahedron letters, 2011 - Elsevier
An efficient preparation of a series of spiro dihydropyridines via one pot four-component
reactions of mono/di/tri-ketones, malononitrile, primary amines, and acetylenic esters is …

Elevating pyrrole derivative synthesis: a three-component revolution

L Kumar S, A Servesh, SJ Chundattu, S Tabassum… - Molecular Diversity, 2024 - Springer
Pyrrole is an essential chemical with considerable relevance as a pharmaceutical
framework for many biologically necessary medications. The growing demand for …

A century-old one-pot multicomponent Biginelli reaction products still finds a niche in drug discoveries: Synthesis, mechanistic studies and diverse biological activities …

S Faizan, TF Roohi, RM Raju, Y Sivamani… - Journal of Molecular …, 2023 - Elsevier
One of the largest classes of organic molecules are dihydropyrimidines and its derivatives.
They are widely used in a variety of pharmacological and industrial applications. Their …

Construction of 1, 4-Dihydropyridines: The Evolution of C4 Source

S Song, Y Wang, F Yu - Topics in Current Chemistry, 2023 - Springer
The field of cascade cyclization for the construction of 1, 4-dihydropyridines (1, 4-DHPs) has
been continuously expanding during the last decades because of their broad-spectrum …