Flutamide as an alternative anti-androgen agent and predictor of the efficacy of novel androgen receptor-targeted agents

N Yamaguchi, S Morizane, T Yumioka… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: There are few reports that verify the relationship between the therapeutic
effects of flutamide and novel androgen receptor-targeted agents. We aimed to evaluate the …

Predictors of poor response to secondary alternative antiandrogen therapy with flutamide in metastatic castration-resistant prostate cancer

M Yasui, K Uemura, S Yoneyama… - Japanese journal of …, 2016 - academic.oup.com
Abstract Objective In Japan, flutamide had been commonly used as second-line alternative
antiandrogen hormonal therapy for metastatic castration-resistant prostate cancer that …

Adrenal androgen levels as predictors of outcome in castration‐resistant prostate cancer patients treated with combined androgen blockade using flutamide as a …

K Narimoto, A Mizokami, K Izumi… - … journal of urology, 2010 - Wiley Online Library
Objectives: To analyze the clinical effects of flutamide as a second‐line anti‐androgen for
combined androgen blockade in patients with castration‐resistant prostate cancer (CRPC) …

The use of flutamide as a single antiandrogen treatment for hormone‐refractory prostate cancer

A Barqawi, B Akduman, Z Abouelfadel… - BJU …, 2003 - Wiley Online Library
OBJECTIVE To investigate the efficacy of low‐dose flutamide (125 mg twice daily) in the
treatment of prostate‐specific antigen (PSA) recurrence after definitive treatment with radical …

Prostate–Specific Antigen Levels and Clinical Response to Flutamide as the Second Hormone Therapy for Hormone–Refractory Prostate Carcinoma

K Fujikawa, Y Matsui, S Fukuzawa, H Takeuchi - European urology, 2000 - karger.com
Background: Some authors have recently reported that maximum androgen block (MAB), in
which the nonsteroidal anti–androgen, flutamide, is used together with conventional …

Alternative antiandrogen therapy with flutamide in patients with castration-resistant prostate cancer: a single center experience

T Takada, Y Ishizuya, T Okada, T Ueda… - Hinyokika kiyo. Acta …, 2011 - europepmc.org
Alternative Antiandrogen Therapy with Flutamide in Patients with Castration-Resistant
Prostate Cancer: A Single Center Experience We analyzed the clinical effects of flutamide …

Recommended Dose of Flutamide with LH‐RH Agonist Therapy in Patients with Advanced Prostate Cancer

H Akaza, S Isaka, M Usami, H Kanetake… - … journal of urology, 1996 - Wiley Online Library
Background: In a recent study by the Casodex Combination Study Group, USA, patients in a
flutamide (750mg/day) plus LH‐RH agonist group showed a high treatment failure rate …

Efficacy of flutamide-combined androgen blockade therapy in advanced prostate cancer patients: a phase III randomized, comparative trial.

H Kanetake, M Usami, Y Ohashi, T Ijima… - Gan to Kagaku ryoho …, 2014 - europepmc.org
The efficacy of combined androgen blockade therapy consisting of flutamide, a nonsteroidal
antiandrogen, plus an LH-RH agonist (F-CAB) was investigated in Japanese patients with …

Clinical outcome of maximum androgen blockade using flutamide as second‐line hormonal therapy for hormone‐refractory prostate cancer

H Miyake, I Hara, H Eto - BJU international, 2005 - Wiley Online Library
OBJECTIVES To investigate the efficacy of maximum androgen blockade (MAB) using
flutamide as second‐line hormonal therapy for advanced hormone‐refractory prostate …

Combination therapy with flutamide: the therapy of choice from early to advanced stages of prostate cancer

F Labrie, A Dupont, L Cusan, JL Gomez… - … in prostate cancer: A …, 1996 - Springer
Among all hormone-sensitive cancers, prostate cancer is recognised as being the most
sensitive. In fact, the best known characteristic of prostate cancer is its marked sensitivity to …