[HTML][HTML] Beta-carboline as a promising heterocyclic nucleus: Synthetic aspects, pharmacological potential and structure activity relationship
Beta-carboline is an indole alkaloid which has been identified as a valuable heterocyclic
nucleus in the field of medicinal chemistry. It has different biological activities like …
nucleus in the field of medicinal chemistry. It has different biological activities like …
Recent Progress for the Synthesis of β-Carboline Derivatives–an Update
The β-Carboline and its derivatives are privileged heterocyclic motifs and important building
blocks in the field of medicinal chemistry due to their remarkable pharmacological …
blocks in the field of medicinal chemistry due to their remarkable pharmacological …
Recent Update on the Anti-infective Potential of β-carboline Analogs
β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of
medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral …
medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral …
A comprehensive overview of β-carbolines and its derivatives as anticancer agents
B Luo, X Song - European Journal of Medicinal Chemistry, 2021 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …
diversity and outstanding antitumor activities. This review summarizes research …
A review of synthetic bioactive tetrahydro-β-carbolines: A medicinal chemistry perspective
J Wang, F Gong, T Liang, Z Xie, Y Yang, C Cao… - European Journal of …, 2021 - Elsevier
Abstract 1, 2, 3, 4-Tetrahydro-β-carboline (THβC) scaffold is widespread in many natural
products (NPs) and synthetic compounds which show a variety of pharmacological activities …
products (NPs) and synthetic compounds which show a variety of pharmacological activities …
[HTML][HTML] Design, synthesis and mechanism of action of novel 1, 9-disubstituted β-carboline derivatives as antitumor agents
F Zhao, J Ao, F Zeng, R Cao, X Li - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract A range of novel 1, 9-disubstituted β-carboline derivatives was designed,
synthesized and evaluated as potential anticancer agents. The preliminary study suggested …
synthesized and evaluated as potential anticancer agents. The preliminary study suggested …
Recent developments on synthesis strategies, SAR studies and biological activities of β-Carboline derivatives–an update
The β-carboline skeleton is prevalent in a vast collection of naturally present alkaloids. Most
of these alkaloids and their derivatives have been found to show significant biological …
of these alkaloids and their derivatives have been found to show significant biological …
β-Carbolines as potential anticancer agents
Abstract β-Carbolines are indole alkaloids having a tricyclic pyrido [3, 4-b] indole ring in their
structure. Since the isolation of first β-carboline from Peganum harmala in 1841, the isolation …
structure. Since the isolation of first β-carboline from Peganum harmala in 1841, the isolation …
β-Carboline alkaloid monomers and dimers: Occurrence, structural diversity, and biological activities
J Dai, W Dan, U Schneider, J Wang - European Journal of Medicinal …, 2018 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with great
structural diversity and outstanding biological activities. This review covers critically …
structural diversity and outstanding biological activities. This review covers critically …
Synthesis Strategies for α‐, β‐, γ‐and δ‐Carbolines
H Zhang, RH Zhang, LX Wang, YJ Li… - Asian Journal of …, 2021 - Wiley Online Library
Carbolines are widely present in various natural products and biological molecules.
Numerous studies have shown the broad biological activities of these heterocyclic motifs …
Numerous studies have shown the broad biological activities of these heterocyclic motifs …