[HTML][HTML] Beta-carboline as a promising heterocyclic nucleus: Synthetic aspects, pharmacological potential and structure activity relationship

M Thatikayala, P Wadhwa, P Kaur, PK Singh… - European Journal of …, 2022 - Elsevier
Beta-carboline is an indole alkaloid which has been identified as a valuable heterocyclic
nucleus in the field of medicinal chemistry. It has different biological activities like …

Recent Progress for the Synthesis of β-Carboline Derivatives–an Update

V Patel, T Bambharoliya, D Shah, Y Patel… - Polycyclic Aromatic …, 2024 - Taylor & Francis
The β-Carboline and its derivatives are privileged heterocyclic motifs and important building
blocks in the field of medicinal chemistry due to their remarkable pharmacological …

Recent Update on the Anti-infective Potential of β-carboline Analogs

BK Kumar, KVGC Sekhar, S Kunjiappan… - Mini reviews in …, 2021 - ingentaconnect.com
β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of
medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral …

A comprehensive overview of β-carbolines and its derivatives as anticancer agents

B Luo, X Song - European Journal of Medicinal Chemistry, 2021 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …

A review of synthetic bioactive tetrahydro-β-carbolines: A medicinal chemistry perspective

J Wang, F Gong, T Liang, Z Xie, Y Yang, C Cao… - European Journal of …, 2021 - Elsevier
Abstract 1, 2, 3, 4-Tetrahydro-β-carboline (THβC) scaffold is widespread in many natural
products (NPs) and synthetic compounds which show a variety of pharmacological activities …

[HTML][HTML] Design, synthesis and mechanism of action of novel 1, 9-disubstituted β-carboline derivatives as antitumor agents

F Zhao, J Ao, F Zeng, R Cao, X Li - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract A range of novel 1, 9-disubstituted β-carboline derivatives was designed,
synthesized and evaluated as potential anticancer agents. The preliminary study suggested …

Recent developments on synthesis strategies, SAR studies and biological activities of β-Carboline derivatives–an update

R Abinaya, S Srinath, S Soundarya, R Sridhar… - Journal of Molecular …, 2022 - Elsevier
The β-carboline skeleton is prevalent in a vast collection of naturally present alkaloids. Most
of these alkaloids and their derivatives have been found to show significant biological …

β-Carbolines as potential anticancer agents

S Aaghaz, K Sharma, R Jain, A Kamal - European Journal of Medicinal …, 2021 - Elsevier
Abstract β-Carbolines are indole alkaloids having a tricyclic pyrido [3, 4-b] indole ring in their
structure. Since the isolation of first β-carboline from Peganum harmala in 1841, the isolation …

β-Carboline alkaloid monomers and dimers: Occurrence, structural diversity, and biological activities

J Dai, W Dan, U Schneider, J Wang - European Journal of Medicinal …, 2018 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with great
structural diversity and outstanding biological activities. This review covers critically …

Synthesis Strategies for α‐, β‐, γ‐and δ‐Carbolines

H Zhang, RH Zhang, LX Wang, YJ Li… - Asian Journal of …, 2021 - Wiley Online Library
Carbolines are widely present in various natural products and biological molecules.
Numerous studies have shown the broad biological activities of these heterocyclic motifs …