Abstract Endothelin-1 (ET-1) is recognized as being involved in the pathophysiology of
cerebrovascular diseases. Using organ culture as a model for possible pathological …

Background and Purpose—Elevated levels of endothelin-1 (ET-1) have been reported in
cerebral ischemia. A role for ET may prove more important if the vascular receptors were …

Endothelins (ET) are a family of 21 amino acid peptides which carry a high degree of
hemology. ET-1, originally isolated from porcine endothelium in culture, is an unusually …

Endothelin (ET) has recently been implicated in the pathogenesis of a variety of
cerebrovascular disorders. In particular, it has been linked to the delayed cerebral …

This report describes the effects of endothelins (ET-1 and ET-3) on ion transport systems
expressed on cultured rat brain capillary endothelial cells (RBEC) and includes investigation …

The vascular effects of endothelins (ET) are in mammals mediated via two receptor
subtypes, endothelin A (ET A, mainly constrictive) and endothelin B (ET B, mainly dilating) …

Background and Purpose—Endothelin-1 (ET) has been shown to be involved in human
pathological conditions, but its physiological function remains to be elucidated. The aim of …

The plasticity of endothelin ET B receptor activity and the influence of pro-inflammatory
cytokines was examined in cerebral artery. In fresh rat basilar artery, the selective ET B …

Abstract ENDOTHELIN-1 (ET-1), a 21-amino acid peptide produced by the vascular
endothelium, mediates contraction. In the present study we demonstrate that both ET-1 (E …

Endothelin (ET) binding sites in male Wistar rat brains subjected to a 20-min four-vessel
occlusion (transient forebrain ischemia model) which induces hip-pocampal neuron death …