Cardiomyocyte and endothelial cells play distinct roles in the tumour necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability …
R Lakin, N Polidovitch, S Yang, M Parikh… - Cardiovascular …, 2023 - academic.oup.com
Aims Endurance exercise is associated with an increased risk of atrial fibrillation (AF). We
previously established that adverse atrial remodelling and AF susceptibility induced by …
previously established that adverse atrial remodelling and AF susceptibility induced by …
Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFα
R Aschar-Sobbi, F Izaddoustdar, AS Korogyi… - Nature …, 2015 - nature.com
Atrial fibrillation (AF) is the most common supraventricular arrhythmia that, for unknown
reasons, is linked to intense endurance exercise. Our studies reveal that 6 weeks of …
reasons, is linked to intense endurance exercise. Our studies reveal that 6 weeks of …
Inhibition of soluble TNFα prevents adverse atrial remodeling and atrial arrhythmia susceptibility induced in mice by endurance exercise
R Lakin, N Polidovitch, S Yang, C Guzman… - Journal of Molecular and …, 2019 - Elsevier
Intense endurance exercise is linked to atrial fibrillation (AF). We established previously that
interventions that simultaneously interfere with TNFα signaling, mediated via both the …
interventions that simultaneously interfere with TNFα signaling, mediated via both the …
Transforming growth factor-β and oxidative stress mediate tachycardia-induced cellular remodelling in cultured atrial-derived myocytes
YH Yeh, CT Kuo, TH Chan, GJ Chang… - Cardiovascular …, 2011 - academic.oup.com
Aims Atrial fibrillation (AF), a common tachyarrhythmia in clinical practice, is associated with
increased oxidative stress. Structural remodelling in atrial myocytes, including myofibril …
increased oxidative stress. Structural remodelling in atrial myocytes, including myofibril …
Role of tumor necrosis factor alpha in the pathogenesis of atrial fibrillation: a novel potential therapeutic target?
M Ren, X Li, L Hao, J Zhong - Annals of medicine, 2015 - Taylor & Francis
Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice and a
major cause of morbidity and mortality. Although the fundamental mechanisms underlying …
major cause of morbidity and mortality. Although the fundamental mechanisms underlying …
Transcriptomic bioinformatic analyses of atria uncover involvement of pathways related to strain and post-translational modification of collagen in increased atrial …
Y Oh, S Yang, X Liu, S Jana, F Izaddoustdar… - Frontiers in …, 2020 - frontiersin.org
Atrial Fibrillation (AF) is the most common supraventricular tachyarrhythmia that is typically
associated with cardiovascular disease (CVD) and poor cardiovascular health …
associated with cardiovascular disease (CVD) and poor cardiovascular health …
Atrial fibrillation promotion by endurance exercise: demonstration and mechanistic exploration in an animal model
E Guasch, B Benito, X Qi, C Cifelli, P Naud… - Journal of the American …, 2013 - jacc.org
Objectives: The goal of this study was to assess mechanisms underlying atrial fibrillation
(AF) promotion by exercise training in an animal model. Background: High-level exercise …
(AF) promotion by exercise training in an animal model. Background: High-level exercise …
Role of tumor necrosis factor-α in the pathogenesis of atrial fibrosis and development of an arrhythmogenic substrate
R Liew, K Khairunnisa, Y Gu, N Tee, NO Yin… - Circulation …, 2013 - jstage.jst.go.jp
Background: Although tumor necrosis factor-α (TNF-α) levels are increased in patients with
atrial fibrillation (AF), its role in the pathogenesis of AF is unclear. We investigated whether …
atrial fibrillation (AF), its role in the pathogenesis of AF is unclear. We investigated whether …
Balanced intense exercise training induces atrial oxidative stress counterbalanced by the antioxidant system and atrial hypertrophy that is not associated with …
Although regular exercise training is associated with cardiovascular benefits, the increased
risk of atrial arrhythmias has been observed after vigorous exercise and has been related to …
risk of atrial arrhythmias has been observed after vigorous exercise and has been related to …
Atrial contractile dysfunction, fibrosis, and arrhythmias in a mouse model of cardiomyopathy secondary to cardiac-specific overexpression of tumor necrosis factor-α
S Saba, AM Janczewski, LC Baker… - American Journal …, 2005 - journals.physiology.org
Transgenic mice overexpressing the inflammatory cytokine TNF-α in the heart develop a
progressive heart failure syndrome characterized by biventricular dilatation, decreased …
progressive heart failure syndrome characterized by biventricular dilatation, decreased …
相关搜索
- endurance exercise arrhythmia susceptibility
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- atrial fibrillation endurance athletes
- atrial hypertrophy exercise training
- endurance exercise mechanistic exploration
- atrial fibrosis tumor necrosis
- involvement of pathways fibrillation vulnerability
- endurance exercise soluble tnfα