Autism spectrum disorder (autism) is a heterogeneous group of neurodevelopmental
conditions characterized by early childhood-onset impairments in communication and social …

The last 25 years have witnessed tremendous changes in our ability to detect autism very
early in life and provide interventions that can significantly influence children's outcomes. It …

Objective: Aside from features associated with risk of neurogenetic syndromes in general
(eg, cognitive impairment), limited progress has been made in identifying phenotype …

Autism spectrum disorder (ASD) consists of a genetically heterogenous group of
neurobehavioral disorders characterized by impairment in three behavioral domains …

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder of
multifactorial origin. Today, ASD is generally not curable, although it is treatable to a varying …

Ten years ago, Francesca Happé and colleagues [2006] argued that it was “time to give up
on a single explanation for autism” because the three core diagnostic domains of autism had …

OBJECTIVE: The primary aim of the present study was to evaluate the validity of proposed
DSM-5 criteria for autism spectrum disorder (ASD). METHOD: We analyzed symptoms from …

This generic, lay definition of heterogeneity provides a descriptive foundation for building a
scientific framework to systematically study heterogeneity in autism. First, autism can be …

The heterogeneous clinical presentations of individuals with autism spectrum disorders
(ASDs) poses a significant challenge for sample characterization and limits the …

Development of standardized diagnostic instruments has facilitated the systematic
characterization of individuals with autism spectrum disorders (ASD) in clinical and research …