The important role of circulating CYFRA21-1 in metastasis diagnosis and prognostic value compared with carcinoembryonic antigen and neuron-specific enolase in …

L Zhang, D Liu, L Li, D Pu, P Zhou, Y Jing, H Yu… - BMC cancer, 2017 - Springer
Background The roles of carcinoembryonic antigen (CEA), cytokeratin 19 fragments
(CYFRA21-1) and neuron-specific enolase (NSE) in metastases occurrence and poor …

Optimal cutoff points of CYFRA21-1 for survival prediction in non-small cell lung cancer patients based on running statistical analysis

H Takahashi, K Kurishima, H Ishikawa… - Anticancer …, 2010 - ar.iiarjournals.org
Purpose: To determine pretreatment serum CYFRA21-1 levels as indicators of poor
prognosis in patients with non-small cell lung cancer (NSCLC). Methods: 1,202 consecutive …

Prognostic impact of Cyfra21-1 and other serum markers in completely resected non-small cell lung cancer

N Reinmuth, B Brandt, M Semik, WP Kunze, R Achatzy… - Lung cancer, 2002 - Elsevier
Purpose: The aim of this prospective study was to assess the prognostic impact of serum
tumor markers (Cyfra21-1, carcinoembryonic antigen, neuron-specific enolase, squamous …

Cyfra 21-1 as a biologic marker of non-small cell lung cancer: evaluation of sensitivity, specificity, and prognostic role

B Wieskopf, C Demangeat, A Purohit, R Stenger… - Chest, 1995 - Elsevier
Background: Cytokeratins are epithelial markers whose expression is not lost during
malignant transformation. Cyfra 21-1 is a cytokeratin-19 fragment that is soluble in serum …

[HTML][HTML] Prognostic value of combination of Cyfra 21-1, CEA and NSE in patients with advanced non-small cell lung cancer

F Barlési, C Gimenez, JP Torre, C Doddoli, J Mancini… - Respiratory …, 2004 - Elsevier
Objective: To assess the value of Cyfra 21-1, carcino-embryonic antigen (CEA) and neuron-
specific enolase (NSE) combined, all three together as prognostic factors in advanced stage …

CYFRA21-1 as a serum tumor marker for follow-up patients with squamous cell lung carcinoma and oropharynx squamous cell carcinoma

L Liu, B Liu, L Zhu, Y Li - Biomarkers in Medicine, 2013 - Future Medicine
Aim: To evaluate serum soluble fragments of cytokeratin 19 (ie, CYFRA21-1) as a tumor
marker for patients with squamous cell lung carcinoma (SCLC) and oropharynx squamous …

[PDF][PDF] Determination of the best prognostic value of serum tumor markers in patients with suspected lung cancer in an Iranian population

N Sigari, B Mohsenpour, B Nikkhoo, B Ghaderi… - Clin Lab, 2014 - researchgate.net
Background: Finding a suitable marker with high sensitivity and specificity for early
diagnosis of cancer is very desirable. This study was aimed to determine the diagnostic …

Evaluation of Cyfra 21-1: a potential tumor marker for non-small cell lung carcinomas

D Karnak, G Ulubay, O Kayacan, S Beder, E Ibis… - Lung, 2001 - Springer
Cyfra 21-1 is a tumor marker based on the determination of water-soluble cytokeratin 19
which is secreted by normal or malignantly transformed epithelial cells. It is suggested to be …

Carcinoembryonic antigen, squamous cell carcinoma antigen, CYFRA 21-1, and neuron-specific enolase in squamous cell lung cancer patients

J Kulpa, E Wojcik, M Reinfuss… - Clinical chemistry, 2002 - academic.oup.com
Abstract Background: Carcinoembryonic antigen (CEA), squamous cell carcinoma antigen
(SCC-Ag), and CYFRA 21-1 are the most useful markers for non-small cell lung cancer …

[HTML][HTML] Declines in serum CYFRA21-1 and carcinoembryonic antigen as predictors of chemotherapy response and survival in patients with advanced non-small cell …

L Yang, X Chen, Y Li, J Yang… - Experimental and …, 2012 - spandidos-publications.com
The aim of this study was to investigate the clinical value of serum cytokeratin 19 fragment
(CYFRA21-1) and carcinoembryonic antigen (CEA) in the prediction of chemotherapy …