H2‐forming methylenetetrahydromethanopterin dehydrogenase (Hmd) is an unusual
hydrogenase present in many methanogenic archaea. The homodimeric enzyme dubbed …

A novel hydrogenase has recently been found in methanogenic archaea. It catalyzes the
reversible dehydrogenation of methylenetetrahydromethanopterin (CH2─ H4MPT) to …

The iron− sulfur-cluster-free hydrogenase Hmd (H2-forming
methylenetetrahydromethanopterin dehydrogenase) from methanogenic archaea has …

The hmd gene, which encodes the metal-free hydrogenase in methanogenic archaea, was
heterologously expressed in Escherichia coli. The overproduced enzyme was completely …

The metal-free hydrogenase from methanogenic archaea (Hmd) is a unique enzyme: it
catalyzes the reaction of its substrate, methenyl-tetrahydromethanopterin, with molecular …

[Fe]-hydrogenase catalyzes the reversible heterolytic cleavage of H2 and stereo-specific
hydride transfer to the substrate methenyltetrahydromethanopterin in methanogenic …

Abstract [Fe]‐hydrogenase functions in the methanogenic pathway of hydrogenotrophic
methanogenic archaea. It catalyzes thereversible reduction of …

Abstract [Fe] hydrogenase (iron–sulfur-cluster-free hydrogenase) catalyzes the reversible
reduction of methenyltetrahydromethanopterin (methenyl-H 4 MPT+) with H 2 to methylene …

Hydrogenases (H 2 ases) are metalloproteins. The great majority of them contain iron-sulfur
clusters and two metal atoms at their active center, either a Ni and an Fe atom, the [NiFe]-H 2 …

Hydrogenases are enzymes that catalyze reversible reactions that have H2 as a substrate or
product. There are three classes of hydrogenases which appear not to be structurally and …