The genetics of behavioral alcohol responses in Drosophila

AR Rodan, A Rothenfluh - International review of neurobiology, 2010 - Elsevier
Drosophila melanogaster is commonly found near rotting or fermenting fruit, reflected in its
name pomace, or vinegar fly. In such environments, flies often encounter significant levels of …

Genetics and genomics of alcohol responses in Drosophila

A Park, A Ghezzi, TP Wijesekera, NS Atkinson - Neuropharmacology, 2017 - Elsevier
Drosophila melanogaster has become a significant model organism for alcohol research. In
flies, a rich variety of behaviors can be leveraged for identifying genes affecting alcohol …

Drosophila melanogaster, a genetic model system for alcohol research

DJ Guarnieri, U Heberlein - 2003 - Elsevier
Publisher Summary The availability of powerful tools for genetic manipulation in Drosophila,
together with the high degree of conservation at the genomic level, make Drosophila a …

The Neurotransmitters Involved in Drosophila Alcohol-Induced Behaviors

MM Chvilicek, I Titos, A Rothenfluh - Frontiers in behavioral …, 2020 - frontiersin.org
Alcohol is a widely used and abused substance with numerous negative consequences for
human health and safety. Historically, alcohol's widespread, non-specific neurobiological …

Addiction-like behavior in Drosophila

AV Devineni, U Heberlein - Communicative & integrative biology, 2010 - Taylor & Francis
Alcohol abuse is a pervasive problem known to be influenced by genetic factors, yet our
understanding of the mechanisms underlying alcohol addiction is far from complete …

Molecular Genetic Analysis of Ethanol Intoxication in Drosophila melanogaster1

U Heberlein, FW Wolf, A Rothenfluh… - Integrative and …, 2004 - academic.oup.com
Recently, the fruit fly Drosophila melanogaster has been introduced as a model system to
study the molecular bases of a variety of ethanol-induced behaviors. It became immediately …

Long-lasting, experience-dependent alcohol preference in Drosophila

SA Ojelade, PS Penninti, RJ Dove, MJ Nye… - Addiction …, 2013 - pmc.ncbi.nlm.nih.gov
To understand the molecular and neural mechanisms underlying alcohol addiction, many
models ranging from vertebrates to invertebrates have been developed. In Drosophila …

Genetic approaches to alcohol addiction: gene expression studies and recent candidates from Drosophila

AA Awofala - Invertebrate Neuroscience, 2011 - Springer
Ethanol intake causes gene expression changes resulting in cellular and molecular
adaptations that could be associated with a predisposition to alcohol dependence. Recently …

The Evolution of Drosophila melanogaster as a Model for Alcohol Research

AV Devineni, U Heberlein - Annual review of neuroscience, 2013 - annualreviews.org
Animal models have been widely used to gain insight into the mechanisms underlying the
acute and long-term effects of alcohol exposure. The fruit fly Drosophila melanogaster …

[HTML][HTML] Genetics of alcohol-induced behaviors in Drosophila

U Heberlein - Alcohol Research & Health, 2000 - ncbi.nlm.nih.gov
Researchers frequently study the fruit fly Drosophila melanogaster as a model system for
mammalian development and behavior. Drosophila appear resistant to alcohol's toxic effects …