A neuroprotective effect of pentoxifylline in rats with diabetic neuropathy: Mitigation of inflammatory and vascular alterations

RAM Salama, FA Raafat, AH Hasanin… - International …, 2024 - Elsevier
Background Treatment of diabetic neuropathic pain does not change the natural history of
neuropathy. Improved glycemic control is the recommended treatment in these cases, given …

[PDF][PDF] Neuroprotecive effect of early treatment with pioglitasone and methylcobalamin in alloxan induced diabetes in rats

AS Morani, SL Bodhankar - Pharmacologyonline, 2007 - pharmacologyonline.silae.it
Neuropathic pain in diabetics is characterized by both hyperalgesia and allodynia. This is
attributed to both uncontrolled glycemia and the further complications which it leads to. We …

Antinociceptive interaction of gabapentin with minocycline in murine diabetic neuropathy

HF Miranda, F Sierralta, V Jorquera, P Poblete… - …, 2017 - Springer
Objective Diabetic neuropathy (DN) is the most common complication of diabetes and pain
is one of the main symptoms of diabetic neuropathy, however, currently available drugs are …

[PDF][PDF] Neuroprotective effect of early treatment with pioglitazone and pyridoxine hydrochloride in alloxan induced diabetes in rats

AS Morani, SL Bodhankar - Pharmacol online, 2007 - researchgate.net
Neuropathic pain in diabetics is characterized by both hyperalgesia and allodynia. This is
attributed to both uncontrolled glycemia and the further complications which it leads to. We …

[HTML][HTML] Pentoxifylline reduces the inflammatory process in diabetic rats: relationship with decreases of pro-inflammatory cytokines and inducible nitric oxide synthase

FAO Garcia, JF Rebouças, TQ Balbino… - Journal of …, 2015 - Springer
Studies suggest that inflammation is a key factor in the pathogenesis of diabetes mellitus.
Pro-inflammatory cytokines, such as IL-6 and TNF-alpha, are produced by adipose tissue in …

[PDF][PDF] Neuroprotective effect of early treatment with pioglitasone and vitamin E acetate in alloxan induced diabetes in rats

AS Morani, SL Bodhankar - Pharmacologyonline, 2007 - pharmacologyonline.silae.it
Neuropathic pain in diabetics is characterized by both hyperalgesia and allodynia. This is
attributed to both uncontrolled glycemia and the further complications which it leads to. We …

[HTML][HTML] Peripheral Nerve Denervation in Streptozotocin-Induced Diabetic Rats Is Reduced by Cilostazol

KY Tseng, HC Wang, YH Wang, MP Su, KF Cheng… - Medicina, 2023 - mdpi.com
Background and Objective: Our previous study demonstrated that consistent treatment of
oral cilostazol was effective in reducing levels of painful peripheral neuropathy in …

The Role of the Inflammatory and the Vascular Pathogenesis in a Model of Streptozotocin Induced Diabetic Neuropathy in Rats

FA Raafat, AH Hasanin, NAF Hendawy… - … Journal of Medicine, 2021 - academic.oup.com
Background Peripheral diabetic neuropathy (DN) is one of the major health problems facing
the whole world. There is no treatment that could completely reverse or prevent progression …

[HTML][HTML] Effect of pentoxifylline on diabetic distal polyneuropathy in type 2 diabetic patients: A randomized trial

F Hosseini, A Mohammadbeigi, M Aghaali… - Journal of Research …, 2019 - journals.lww.com
Background: Diabetes is one of the most common causes of peripheral neuropathy. There
are no known cures for diabetic neuropathy. Pentoxifylline could theoretically be a beneficial …

Preventive role of metformin on peripheral neuropathy induced by diabetes

DB Lós, WH de Oliveira, E Duarte-Silva… - International …, 2019 - Elsevier
Metformin is the first line drug in the treatment of type 2 diabetes, however, little is known
about its therapeutic potential to prevent or delay damage to the peripheral nerve. Thus, the …