Topographic cue from electrospun scaffolds regulate myelin-related gene expressions in Schwann cells

J Radhakrishnan, AA Kuppuswamy… - Journal of …, 2015 - ingentaconnect.com
Matured Schwann cells play a vital role in promoting regeneration and restoration of
functional peripheral nervous tissue. In the present study, two dimensional film, three …

The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation

SY Chew, R Mi, A Hoke, KW Leong - Biomaterials, 2008 - Elsevier
Peripheral nerve regeneration can be enhanced by the stimulation of formation of bands of
Büngner prior to implantation. Aligned electrospun poly (ε-caprolactone)(PCL) fibers were …

Fabrication of uniaxially aligned 3D electrospun scaffolds for neural regeneration

A Subramanian, UM Krishnan… - Biomedical …, 2011 - iopscience.iop.org
Nanofibrous scaffolds are very promising physical guidance substrates for regenerating
nerves to traverse larger nerve gaps. In this study, we have attempted to develop 2D random …

The effect of electrospun gelatin fibers alignment on schwann cell and axon behavior and organization in the perspective of artificial nerve design

S Gnavi, BE Fornasari, C Tonda-Turo… - International Journal of …, 2015 - mdpi.com
Electrospun fibrous substrates mimicking extracellular matrices can be prepared by
electrospinning, yielding aligned fibrous matrices as internal fillers to manufacture artificial …

Fabrication of alignment polycaprolactone scaffolds by combining use of electrospinning and micromolding for regulating Schwann cells behavior

L Zhang, S Chen, R Liang, Y Chen, S Li… - … Research Part A, 2018 - Wiley Online Library
In the present study, a new approach for fabricating micropatterned polycaprolactone (PCL)
scaffolds with ridge/groove structure on the surface was developed by combining use of …

Effects of PLGA nanofibrous scaffolds structure on nerve cell directional proliferation and morphology

F Zamani, M Latifi, M Amani-Tehran… - Fibers and Polymers, 2013 - Springer
Electrospinning has been recognized as an efficient technique for the fabrication of neural
tissue engineering scaffolds. Many approaches have been developed on material …

Nerve growth factor (NGF)-conjugated electrospun nanostructures with topographical cues for neuronal differentiation of mesenchymal stem cells

YI Cho, JS Choi, SY Jeong, HS Yoo - Acta biomaterialia, 2010 - Elsevier
Mesenchymal stem cells (MSCs) were cultivated on the surface of nerve growth factor (NGF)-
conjugated aligned nanofibrous meshes for neuronal differentiation. Amine-terminated poly …

Aligned and random nanofibrous substrate for the in vitro culture of Schwann cells for neural tissue engineering

D Gupta, J Venugopal, MP Prabhakaran, VRG Dev… - Acta biomaterialia, 2009 - Elsevier
The current challenge in peripheral nerve tissue engineering is to produce an implantable
scaffold capable of bridging long nerve gaps that will produce results similar to autograft …

Oriented growth of rat Schwann cells on aligned electrospun poly (methyl methacrylate) nanofibers

H Xia, X Sun, D Liu, Y Zhou, D Zhong - Journal of the neurological …, 2016 - Elsevier
Transplanted Schwann cells have the potential to serve as a support for regenerating
neurites after spinal cord injury. However, implanted Schwann cells die off rapidly once …

The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation

GT Christopherson, H Song, HQ Mao - Biomaterials, 2009 - Elsevier
Neural stem/progenitor cells (NSCs) are capable of self-renewal and differentiation into all
types of neural lineage under different biochemical and topographical cues. In this study, we …