Objectives The objective of this study was to characterize the underlying molecular
mechanisms in consecutive clinical Candida albicans isolates from a single patient …

Objectives MDR Candida strains are emerging. Next-generation sequencing (NGS), which
enables extensive and deep genome analysis, was used to investigate echinocandin and …

Introduction/Objectives An increase in antifungal resistant Candida strains has been
reported in recent years. The aim of this study was to detect mutations in resistance genes of …

Candida albicans is both a member of the healthy human microbiome and a major pathogen
in immunocompromised individuals. Infections are typically treated with azole inhibitors of …

Objectives Increasing incidence of azole resistance in Candida tropicalis, especially to
fluconazole, has been seen in Asian countries including India. Limited knowledge is …

Background Antifungal resistance rates are increasing. We investigated the mechanisms of
azole resistance of Candida spp. bloodstream isolates obtained from a surveillance study …

Multidrug resistance (MDR) has emerged in hospitals due to the use of several agents
administered in combination or sequentially to the same individual. We reported earlier …

Abstract Background The genome of Candida albicans displays significant polymorphism.
Point mutations in genes involved in resistance to antifungals may either confer phenotypic …

The activity of 7 antifungal agents against 3,557 invasive yeasts and molds collected in 29
countries worldwide in 2014 and 2015 was evaluated. Epidemiological cutoff values (ECVs) …

Objectives Multi-antifungal drug resistance in Candida glabrata is increasing. We examined
the feasibility of next-generation sequencing (NGS) to investigate the presence of antifungal …