Stroke is the leading cause of morbidity and mortality in patients with atrial fibrillation.
Whereas warfarin reduces the risk of stroke, its interactions with other drugs and food …

Atrial fibrillation (AF) is considered to be one of the most prevalent abnormal heart rhythm
disorders and a leading cause of cerebral ischemia. The risk of stroke in AF is associated …

Importance of the field: Warfarin is the only oral anticoagulant recommended for the
prevention of ischemic stroke in atrial fibrillation. A newer and safer anticoagulant is needed …

Vitamin K antagonists have been the standard in stroke prophylaxis in patients with atrial
fibrillation for decades, but several limitations make it difficult for patients to tolerate chronic …

Atrial fibrillation (AF) is an independent major risk factor for stroke, and antithrombotic
therapy is here recommended according to stratification of the patient's thromboembolic and …

Ischemic stroke is arguably the most feared complication of atrial fibrillation. While warfarin
has been the most effective pharmacologic treatment for stroke prevention in patients with …

Dabigatran is an oral thrombin inhibitor which has been approved in several countries as an
alternative to vitamin-K-antagonists for the prevention of stroke or embolism in atrial …

Oral anticoagulation is the mainstay of therapy for stroke prevention in patients with atrial
fibrillation. Vitamin K antagonists such as warfarin reduce the risk of cardioembolic stroke by …

The need for safe, effective and easily administered and monitored anti-thrombotic
treatments that do not have the issues common to warfarin treatment has led to the …

The incidence of atrial fibrillation (AF) is growing at an increasing rate and presents major
health problems due to its high association with stroke and systemic embolism …