Extracellular matrix regulation in the muscle satellite cell niche

K Thomas, AJ Engler, GA Meyer - Connective tissue research, 2015 - Taylor & Francis
Increasing evidence points to extracellular matrix (ECM) components playing integral roles
in regulating the muscle satellite cell (SC) niche. Even small alterations to the niche ECM …

Muscle stem cells and aging

AB Hwang, AS Brack - Current topics in developmental biology, 2018 - Elsevier
Satellite cells (SCs) are a population of muscle-resident stem cells that are essential for
efficient tissue repair. SCs reside in a relatively quiescent state during normal tissue …

[HTML][HTML] Stem cell and macrophage roles in skeletal muscle regenerative medicine

P Scala, L Rehak, V Giudice, E Ciaglia… - International Journal of …, 2021 - mdpi.com
In severe muscle injury, skeletal muscle tissue structure and functionality can be repaired
through the involvement of several cell types, such as muscle stem cells, and innate immune …

[HTML][HTML] Lineage tracing reveals a subset of reserve muscle stem cells capable of clonal expansion under stress

A Scaramozza, D Park, S Kollu, I Beerman, X Sun… - Cell stem cell, 2019 - cell.com
Stem cell heterogeneity is recognized as functionally relevant for tissue homeostasis and
repair. The identity, context dependence, and regulation of skeletal muscle satellite cell (SC) …

Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease

AE Almada, AJ Wagers - Nature reviews Molecular cell biology, 2016 - nature.com
Satellite cells are adult myogenic stem cells that repair damaged muscle. The enduring
capacity for muscle regeneration requires efficient satellite cell expansion after injury, their …

Cellular players in skeletal muscle regeneration

LC Ceafalan, BO Popescu… - BioMed research …, 2014 - Wiley Online Library
Skeletal muscle, a tissue endowed with remarkable endogenous regeneration potential, is
still under focused experimental investigation mainly due to treatment potential for muscle …

[HTML][HTML] Adult stem cells at work: regenerating skeletal muscle

M Schmidt, SC Schüler, SS Hüttner, B von Eyss… - Cellular and Molecular …, 2019 - Springer
Skeletal muscle regeneration is a finely tuned process involving the activation of various
cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are …

[HTML][HTML] Towards stem cell therapies for skeletal muscle repair

RN Judson, FMV Rossi - NPJ Regenerative medicine, 2020 - nature.com
Skeletal muscle is an ideal target for cell therapy. The use of its potent stem cell population
in the form of autologous intramuscular transplantation represents a tantalizing strategy to …

[HTML][HTML] Decellularised skeletal muscles allow functional muscle regeneration by promoting host cell migration

A Urciuolo, L Urbani, S Perin, P Maghsoudlou… - Scientific reports, 2018 - nature.com
Pathological conditions affecting skeletal muscle function may lead to irreversible volumetric
muscle loss (VML). Therapeutic approaches involving acellular matrices represent an …

Regulatory factors and cell populations involved in skeletal muscle regeneration

RW Ten Broek, S Grefte… - Journal of cellular …, 2010 - Wiley Online Library
Skeletal muscle regeneration is a complex process, which is not yet completely understood.
Satellite cells, the skeletal muscle stem cells, become activated after trauma, proliferate, and …