The increasing prevalence of obesity is accompanied by a rising incidence in metabolic
syndrome and related pathologies such as non-alcoholic fatty liver disease. Macrophages …

Obesity is associated with the development of metabolic diseases such as type 2 diabetes
and non-alcoholic fatty liver disease. The presence of chronic, low-grade inflammation …

The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …

Growing evidence places tissue-resident macrophages as essential gatekeepers of
metabolic organ homeostasis, including the adipose tissue and the pancreatic islets …

Macrophage infiltration into adipose tissue is a key pathological factor inducing adipose
tissue dysfunction and contributing to obesity-induced inflammation and metabolic …

In obesity, chronic low-grade inflammation is thought to mediate the effects of increased
adipose tissue mass on metabolic comorbidity. Of the different cell types that contribute to …

Obesity is causally linked to a chronic state of “low-grade” inflammation in adipose tissue.
Prolonged, unremitting inflammation in this tissue has a direct impact on insulin-sensitive …

Obesity has become a worldwide epidemic that poses a severe threat to human health.
Evidence suggests that many obesity comorbidities, such as type 2 diabetes mellitus …

Obesity is a complex metabolic disorder associated with the development of non-
communicable diseases such as cirrhosis, non-alcoholic fatty liver disease, and type 2 …

Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable
plasticity and play pivotal roles in coordinating immune responses and maintaining tissue …