Proteoglycans are ubiquitous cell-surface and secreted glycoproteins that are involved in
diverse cellular behaviors. The identities of several nervous system Proteoglycans, including …

Cellular interactions in neural development are influenced by various extracellular proteins,
many of which bind glycosaminoglycans or proteoglycans. Precise functions of nervous …

Proteoglycans are a heterogeneous class of proteins bearing sulfated glycosaminoglycans.
Some of the proteoglycans have distinct core protein structures, and others display …

Proteoglycans are diverse, complex extracellular/cell surface macromolecules composed of
a central core protein with covalently linked glycosaminoglycan (GAG) chains; both of these …

Large numbers of different proteoglycans are expressed in tightly regulated spatio-temporal
patterns by both the nerve cells (neurons) and the supporting glial cells of the nervous …

The occurrence of multiple proteoglycan species is a characteristic of the brain. The
structural features of individually characterized proteoglycans in the brain are first introduced …

A number of studies have demonstrated that the nervous system produces multiple
molecular species of proteoglycans (PGs), and that these PGs on cell surfaces and in the …

Proteoglycans (PGs) are major components of the cell surface and extracellular matrix and
play critical roles in development and maintenance of the central nervous system (CNS) …

The proteoglycans are multifunctional macromolecules composed of a core polypeptide and
a variable number of glycosaminoglycan chains. The structural diversity and complexities of …

Proteoglycans (PGs) are a diverse group of macromolecules found in the extracellular matrix
(ECM) and on the surface of cells. They have been shown to be coreceptors for several …