The aim of this systematic review was to investigate the studies that evaluated the sensitivity
and specificity of serologic tests using recombinant protein antigens from Mycobacterium …

IgM against Mycobacterium leprae may be detected by enzyme-linked immunosorbent
assays (ELISAs) based on phenolic glycolipid I (PGL-I) or natural disaccharide octyl bovine …

New Mycobacterium leprae protein antigens can contribute to improved serologic tests for
leprosy diagnosis/classification and multidrug therapy (MDT) monitoring. This study …

Introduction: Despite the effectiveness of multidrug therapy, leprosy still represents a
significant global health problem: transmission of Mycobacterium leprae (M. leprae) is not …

Till 2010, several countries have declared less than one leprosy patient among population
of 10,000 and themselves feeling as eliminated from leprosy cases. However, new leprosy …

Diagnostic tests for leprosy are limited, especially to identify early leprosy cases. We
performed active case finding of leprosy to validate three potential antigen candidates and …

Leprosy can be a devastating chronic infection that causes nerve function impairment and
associated disfigurement. Despite the recent reduction in the number of registered …

Although worldwide leprosy prevalence has been reduced considerably following multidrug
therapy, new case detection rates remain relatively stable, suggesting that transmission of …

Leprosy remains an important health problem in a number of regions. Early detection of
infection, followed by effective treatment, is critical to reduce disease progression. New …

Introduction: In the Americas, Brazil contributes 91.63% of the total cases and the state of
Pará still has high endemia for leprosy. Objective: To analyze the performance of a rapid test …