Eslicarbazepine acetate in the treatment of adults with partial-onset epilepsy: an evidence-based review of efficacy, safety and place in therapy

S Lattanzi, F Brigo, C Cagnetti, A Verrotti… - Core …, 2018 - Taylor & Francis
Introduction: Up to 30% of the patients diagnosed with epilepsy will continue suffering from
seizures despite treatment with antiepileptic drugs, either in monotherapy or polytherapy …

Eslicarbazepine acetate: a double‐blind, add‐on, placebo‐controlled exploratory trial in adult patients with partial‐onset seizures

C Elger, M Bialer, JA Cramer, J Maia, L Almeida… - …, 2007 - Wiley Online Library
Objective: To explore the efficacy and safety of eslicarbazepine acetate (BIA 2‐093), a new
antiepileptic drug, as adjunctive therapy in adult patients with partial epilepsy. Methods: A …

Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy

E Ben-Menachem, AA Gabbai, A Hufnagel, J Maia… - Epilepsy research, 2010 - Elsevier
OBJECTIVE: To investigate the efficacy and safety of once-daily eslicarbazepine acetate
(ESL) when used as add-on treatment in adults with≥ 4 partial-onset seizures per 4-week …

Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures

A Gil‐Nagel, J Lopes‐Lima, L Almeida… - Acta Neurologica …, 2009 - Wiley Online Library
Objectives–To evaluate the efficacy and safety of eslicarbazepine acetate (ESL) as
adjunctive therapy in adults with partial‐onset seizures. Material and methods–Double …

Long-term safety and efficacy of eslicarbazepine acetate as adjunctive therapy in the treatment of partial-onset seizures in adults with epilepsy: results of a 1-year …

A Hufnagel, E Ben-Menachem, AA Gabbai, A Falcão… - Epilepsy Research, 2013 - Elsevier
OBJECTIVE: To evaluate the long-term safety, tolerability and efficacy of once-daily
eslicarbazepine acetate (ESL) as adjunctive therapy in adults with partial-onset seizures …

Efficacy and safety of eslicarbazepine acetate as add‐on treatment in patients with focal‐onset seizures: integrated analysis of pooled data from double‐blind phase III …

A Gil‐Nagel, C Elger, E Ben‐Menachem, P Halász… - …, 2013 - Wiley Online Library
Purpose: To evaluate the efficacy and safety profile of eslicarbazepine acetate (ESL) added
to stable antiepileptic therapy in adults with partial‐onset seizures. Methods: Data from …

Eslicarbazepine acetate as adjunctive therapy in patients with uncontrolled partial‐onset seizures: results of a phase III, double‐blind, randomized, placebo‐controlled …

MR Sperling, B Abou‐Khalil, J Harvey, JB Rogin… - …, 2015 - Wiley Online Library
Objective To evaluate the efficacy and safety of adjunctive eslicarbazepine acetate (ESL) in
patients with refractory partial‐onset seizures. Methods This randomized, placebo …

Eslicarbazepine acetate for the treatment of focal epilepsy: an update on its proposed mechanisms of action

P Soares‐da‐Silva, N Pires… - Pharmacology …, 2015 - Wiley Online Library
Eslicarbazepine acetate (ESL) is a once daily antiepileptic drug (AED) approved by the
European Medicines Agency (EMA), the Food and Drug Administration (FDA) and Health …

Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures: a randomized, double‐blind, placebo‐controlled …

C Elger, P Halász, J Maia, L Almeida… - …, 2009 - Wiley Online Library
Purpose: To study the efficacy and safety of eslicarbazepine acetate (ESL) as adjunctive
therapy for refractory partial seizures in adults with≥ 4 partial‐onset seizures (simple or …

Pooled efficacy and safety of eslicarbazepine acetate as add‐on treatment in patients with focal‐onset seizures: Data from four double‐blind placebo‐controlled …

C Elger, M Koepp, E Trinka… - CNS Neuroscience …, 2017 - Wiley Online Library
Purpose Pooled evaluation of the key efficacy and safety profile of eslicarbazepine acetate
(ESL) added‐on to stable antiepileptic therapy in adults with focal‐onset seizures. Methods …