Recent advances in the pharmacological management of sepsis-associated acute kidney injury

K Kalantari, MH Rosner - Expert Review of Clinical Pharmacology, 2021 - Taylor & Francis
Introduction Acute kidney injury is a common occurrence in patients with sepsis and
portends a high mortality as well as increased morbidity with numerous sequelae including …

Update on sepsis-associated acute kidney injury: emerging targeted therapies

JF Doyle, LG Forni - Biologics: Targets and Therapy, 2016 - Taylor & Francis
Sepsis-associated acute kidney injury (SA-AKI) is an independent predictor of increased
mortality and morbidity. It is essential that further advances in the treatment of sepsis should …

Emerging therapeutic targets of sepsis-associated acute kidney injury

S Swaminathan, MH Rosner, MD Okusa - Seminars in nephrology, 2015 - Elsevier
Sepsis-associated acute kidney injury (SA-AKI) is linked to high morbidity and mortality. To
date, singular approaches to target specific pathways known to contribute to the …

Sepsis and acute kidney injury

A Zarjou, A Agarwal - Journal of the American Society of …, 2011 - journals.lww.com
Sepsis is a severe and dysregulated inflammatory response to infection characterized by
end-organ dysfunction distant from the primary site of infection. Development of acute kidney …

[HTML][HTML] Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

S Peerapornratana, CL Manrique-Caballero… - Kidney international, 2019 - Elsevier
Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

[HTML][HTML] Biomarkers, diagnosis and management of sepsis-induced acute kidney injury: a narrative review

Z Zhang - Heart, lung and vessels, 2015 - ncbi.nlm.nih.gov
Sepsis is a leading cause of acute kidney injury in clinical practice. The diagnosis of sepsis-
induced acute kidney injury requires the diagnosis of sepsis and subsequent occurrence of …

Acute Kidney Injury in Sepsis

RW Schrier, S Bansal, W Wang - Management of Acute Kidney Problems, 2010 - Springer
Sepsis is the most common cause of acute kidney injury (AKI) in the intensive care unit.
Mortality of AKI is much higher in septic patients compared with nonseptic patients. Septic …

Pathophysiology of septic acute kidney injury

J Mårtensson, R Bellomo - Acute Kidney Injury-From Diagnosis to Care, 2016 - karger.com
Background: Despite increased understanding of the pathophysiology of septic acute kidney
injury (AKI), treatment options are limited, and mortality remains high. Summary: Septic AKI …

Potential interventions in sepsis-related acute kidney injury

C Ronco, JA Kellum, R Bellomo… - Clinical journal of the …, 2008 - journals.lww.com
Sepsis is an important cause of morbidity and mortality. Acute kidney injury often
complicates sepsis, leading to greater complexity, cost of care, and worsening prognosis. In …

[HTML][HTML] Sepsis-associated acute kidney injury

D Wang, T Sun, Z Liu - Intensive Care Research, 2023 - Springer
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
immune response to infection. The kidneys are one of the first organs to be injured in sepsis …