The inversion enzymes of the FimI system of E. coli also belong to the integrase family.
Since the biological function of this genetic switch resembles that promoted by the members …

Site-specific recombinases of the integrase family usually require cofactors to impart
directionality in the recombination reactions that they catalyze. The FimB integrase inverts …

The FimB protein is a site-specific recombinase that inverts the fimS genetic switch in
Escherichia coli. Based on amino acid sequence analysis alone, FimB has been assigned to …

Specialized recombination reactions involving DNA inversions have evolved as a
mechanism to generate genetic diversity within a population. They often function to preadapt …

Bacteriophage λ integrase (Int) is a versatile site-specific recombinase. In concert with other
proteins, it mediates phage integration into and excision out of the bacterial chromosome. Int …

Phase variable expression of type 1 fimbriae in Escherichia coli arises from a site‐specific
recombination event that inverts a short segment of chromosomal DNA carrying the …

Site‐specific inversion of the G segment in phage Mu DNA is promoted by two proteins, the
DNA invertase Gin and the host factor FIS. Recombination occurs if the recombination sites …

In hope of discovering universal biochemical mechanisms underlying these important
processes, several groups have followed the lead of Nash and colleagues (53) and have …

Site‐specific DNA inversion in phage Mu is catalysed by the phage‐encoded DNA invertase
Gin and a host factor FIS. We demonstrate that purified Gin protein binds specifically to 34 …

During lysogenic growth many temperate bacteriophage genomes are integrated into the
host's chromosome and efficient integration and excision are therefore an essential part of …