Genetics of intracranial aneurysms

BV Nahed, M Bydon, AK Ozturk, K Bilguvar… - …, 2007 - journals.lww.com
Abstract DESPITE ADVANCES IN the treatment of intracranial aneurysms (IA) in recent
years, the overall outcome of patients with aneurysmal subarachnoid hemorrhage has …

Epidemiology and genetics of intracranial aneurysms

F Caranci, F Briganti, L Cirillo, M Leonardi… - European journal of …, 2013 - Elsevier
Intracranial aneurysms are acquired lesions (5–10% of the population), a fraction of which
rupture leading to subarachnoid hemorrhage with devastating consequences. Until now, the …

Genetic basis of intracranial aneurysm formation and rupture: clinical implications in the postgenomic era

N Samuel, I Radovanovic - Neurosurgical focus, 2019 - thejns.org
OBJECTIVE Despite the prevalence and impact of intracranial aneurysms (IAs), the
molecular basis of their pathogenesis remains largely unknown. Moreover, there is a dearth …

The genetics of intracranial aneurysms

B Krischek, I Inoue - Journal of human genetics, 2006 - nature.com
The rupture of an intracranial aneurysm (IA) leads to a subarachnoid hemorrhage, a sudden
onset disease that can lead to severe disability and death. Several risk factors such as …

Molecular genetics of human intracranial aneurysms

J Zhang, RE Claterbuck - International Journal of Stroke, 2008 - journals.sagepub.com
Intracranial aneurysms (IAs) are the dilatations of blood vessels in the brain and pose
potential risk of rupture leading to subarachnoid hemorrhage. Although the genetic basis of …

The familial intracranial aneurysm (FIA) study protocol

JP Broderick, LR Sauerbeck, T Foroud, J Huston… - BMC Medical …, 2005 - Springer
Background Subarachnoid hemorrhage (SAH) due to ruptured intracranial aneurysms (IAs)
occurs in about 20,000 people per year in the US annually and nearly half of the affected …

Genetic investigations on intracranial aneurysm: update and perspectives

R Bourcier, R Redon, H Desal - Journal of Neuroradiology, 2015 - Elsevier
Detection of an intracranial aneurysm (IA) is a common finding in MRI practice. Nowadays,
the incidence of unruptured IA seems to be increasing with the continuous evolution of …

Genetics of intracranial aneurysms

MK Bakker, YM Ruigrok - Stroke, 2021 - Am Heart Assoc
Rupture of an intracranial aneurysm leads to aneurysmal subarachnoid hemorrhage, a
severe type of stroke which is, in part, driven by genetic variation. In the past 10 years …

Understanding the pathophysiology of intracranial aneurysm: the ICAN project

R Bourcier, S Chatel, E Bourcereau, S Jouan… - …, 2017 - journals.lww.com
BACKGROUND: Understanding the pathophysiologic mechanism of intracranial aneurysm
(IA) formation is a prerequisite to assess the potential risk of rupture. Nowadays, there are …

Genetics of intracranial aneurysms

YM Ruigrok, GJE Rinkel - Stroke, 2008 - Am Heart Assoc
Background and Purpose—Genetic determinants probably play a role in the development of
intracranial aneurysms. We review the present knowledge on this issue. Methods—This …