Emodin is an active monomer extracted from rhubarb root, which has many biological
functions, including anti‐inflammation, antioxidation, anticancer, and neuroprotection …

Aberrant activation of histone lysine-specific demethylase (LSD1) increases tumorigenicity;
hence, LSD1 is considered a therapeutic target for various human cancers. Although …

Thanks to advances in cancer treatment, the survival of cancer patients has increased
significantly. According to the American Cancer Society, in 2022,∼ 47% of cancer patients …

Hypoxia is a crucial factor in tumor aggressiveness and resistance to therapy, especially in
glioblastoma. Our previous results have shown that melatonin exerts antimigratory and anti …

Background Obstructive sleep apnea (OSA) is associated with increased risk of lung cancer
mortality. Nevertheless, little is known about the underlying molecular mechanisms. This …

GBM is the most threatening form of brain tumor. The advancement of GBM is propelled by
the growth, infiltration, and movement of cancer cells. Understanding the underlying …

Background Poor sleep quality and even insomnia are global problems, especially after the
COVID-19 pandemic, and bioactive substances in natural herbal medicines may improve …

Introduction Sleep deprivation (SD) is a common disorder in modern society. Hippocampus
is an important region of the brain for learning, memory, and emotions. Dysfunction of …

Due to the steadily rising morbidity and mortality, thyroid cancer remains the most commonly
seen endocrine cancer. The present study attempted to investigate the mechanism from the …

Sleep disruption ranks among the most common complaints of breast cancer patients
undergoing chemotherapy. Because of the complex interactions among cancer, treatment …