Clinical proteomics in cancer research-promises and limitations of current two-dimensional gel electrophoresis

Y Iwadate - Current medicinal chemistry, 2008 - ingentaconnect.com
Cancer can be defined as a deviated protein network system toward dysregulated cellular
proliferation. Alteration in the content and functional state of the proteins with many linkages …

Advanced proteomic technologies for cancer biomarker discovery

SCC Wong, CML Chan, BBY Ma… - Expert review of …, 2009 - Taylor & Francis
Proteomic technologies have experienced major improvements in recent years. Such
advances have facilitated the discovery of potential tumor markers with improved …

Cancer Proteomics: New Developments in Clinical Chemistry. Krebs-„Proteomics": Neue Entwicklungen in der klinischen Chemie

AJ Rai, DW Chan - LaboratoriumsMedizin/Journal of Laboratory …, 2001 - degruyter.com
The entire protein complement of a cell is termed the proteome." Proteomics" is defined as
the systematic expression of diverse properties of proteins in a cell. Proteomic …

Quantitative proteomics and biomarker discovery in human cancer

Y Zhao, WNP Lee, GG Xiao - Expert review of proteomics, 2009 - Taylor & Francis
Early diagnosis and prevention is crucial for reducing the mortality and morbidity of cancer.
Current clinical examination, such as mammography and invasive needle or surgical …

Current perspectives in cancer proteomics

MV Dwek, SL Rawlings - Molecular biotechnology, 2002 - Springer
Proteome technology has been used widely in cancer research and is a useful tool for the
identification of new cancer markers and treatment-related changes in cancer. This article …

[PDF][PDF] Proteomic approaches in biological and medical sciences: principles and applications

P Conrotto, S Souchelnytskyi - Exp. Oncol, 2008 - academia.edu
After the first introduction of the concept of “proteome” more than 10 years ago, large-scale
studies of protein expression, localization, activities and interactions have gained an …

Proteomics approaches in the identification of cancer biomarkers and drug discovery

N Nisar, SA Mir, O Kareem, FH Pottoo - Proteomics, 2023 - Elsevier
Proteomics is the study which involves analyzing proteins from both a basic science and a
clinical perspective. Proteins can be assessed for abundance, diversity of proteoforms owing …

Contributions of advanced proteomics technologies to cancer diagnosis

S Ciordia, V Ríos, JP Albar - Clinical and Translational Oncology, 2006 - Springer
The ability of Medicine to effectively treat and cure cancer is directly dependent on their
capability to detect cancers at their earliest stages. The advent of proteomics has brought …

Proteomic strategies and their application in cancer research

R Alessandro, S Fontana, E Kohn… - Tumori Journal, 2005 - journals.sagepub.com
The understanding of carcinogenesis and tumor progression on a molecular basis needs a
detailed study of proteins as effector molecules and as critical components of the multiple …

Application of proteomics in cancer gene profiling: two-dimensional difference in gel electrophoresis (2D-DIGE)

D Hariharan, ME Weeks… - Cancer Gene Profiling …, 2010 - Springer
In the post-genomic era, proteomic strategies are at the forefront of cancer research. By
studying the complement of all expressed genes, proteomics aims to provide knowledge of …